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Page 16 of 28                                               Cheng et al. Cancer Drug Resist. 2025;8:46

























































































               Figure 6. (A) Albumin-templated manganese dioxide nanoparticles loaded with triphenylphosphine-derived metformin via positive and
               negative adsorption to form a hybrid nanoadjuvant; (B) These nanoparticles synergized with radiotherapy to elicit antitumor
               immunological memory.  P <​ 0.01,  P <​ 0.001 [reproduced with permission from Yi et al. (2024) [157] . Copyright 2024 John Wiley and
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               Sons].                                      16
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