Page 19 - Read Online

Page 10 of 13 Li et al. Ageing Neur Dis 2022;2:12 https://dx.doi.org/10.20517/and.2022.14

23. Sorrells SF, Paredes MF, Cebrian-Silla A, et al. Human hippocampal neurogenesis drops sharply in children to undetectable levels in
adults. Nature 2018;555:377-81. DOI PubMed PMC
24. Eriksson PS, Perfilieva E, Björk-Eriksson T, et al. Neurogenesis in the adult human hippocampus. Nat Med 1998;4:1313-7. DOI
PubMed
25. Fang R, Xia C, Close JL, et al. Conservation and divergence of cortical cell organization in human and mouse revealed by MERFISH.
Science 2022;377:56-62. DOI PubMed PMC
26. Chen A, Liao S, Cheng M, et al. Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays.
Cell 2022;185:1777-1792.e21. DOI PubMed
27. Han L, Wei X, Liu C, et al. Cell transcriptomic atlas of the non-human primate Macaca fascicularis. Nature 2022;604:723-31. DOI
PubMed
28. Hickman S, Izzy S, Sen P, Morsett L, El Khoury J. Microglia in neurodegeneration. Nat Neurosci 2018;21:1359-69. DOI PubMed
PMC
29. Lee HG, Wheeler MA, Quintana FJ. Function and therapeutic value of astrocytes in neurological diseases. Nat Rev Drug Discov
2022;21:339-58. DOI PubMed PMC
30. Bernhardi R, Eugenin-von Bernhardi L, Eugenin J. Microglial cell dysregulation in brain aging and neurodegeneration. Front Aging
Neurosci 2015;7:124. DOI PubMed PMC
31. Taber KH, Hurley RA. Astroglia: not just glue. J Neuropsychiatry Clin Neurosci 2008;20:iv-129. DOI PubMed
32. Geirsdottir L, David E, Keren-Shaul H, et al. Cross-species single-cell analysis reveals divergence of the primate microglia program.
Cell 2020;181:746. DOI PubMed
33. Matyash V, Kettenmann H. Heterogeneity in astrocyte morphology and physiology. Brain Res Rev 2010;63:2-10. DOI PubMed
34. Rash BG, Duque A, Morozov YM, Arellano JI, Micali N, Rakic P. Gliogenesis in the outer subventricular zone promotes
enlargement and gyrification of the primate cerebrum. Proc Natl Acad Sci U S A 2019;116:7089-94. DOI PubMed PMC
35. Falcone C, Wolf-Ochoa M, Amina S, et al. Cortical interlaminar astrocytes across the therian mammal radiation. J Comp Neurol
2019;527:1654-74. DOI PubMed PMC
36. Oberheim NA, Wang X, Goldman S, Nedergaard M. Astrocytic complexity distinguishes the human brain. Trends Neurosci
2006;29:547-53. DOI PubMed
37. Xu R, Zanotti-Fregonara P, Zoghbi SS, et al. Synthesis and evaluation in monkey of [(18)F]4-fluoro-N-methyl-N-(4-(6-
(methylamino)pyrimidin-4-yl)thiazol-2-yl)benzamide ([(18)F]FIMX): a promising radioligand for PET imaging of brain
metabotropic glutamate receptor 1 (mGluR1). J Med Chem 2013;56:9146-55.
38. Knox EG, Aburto MR, Clarke G, Cryan JF, O'Driscoll CM. The blood-brain barrier in aging and neurodegeneration. Mol Psychiatry
2022;27:2659-73. DOI PubMed PMC
39. Pike VW. PET radiotracers: crossing the blood-brain barrier and surviving metabolism. Trends Pharmacol Sci 2009;30:431-40. DOI
PubMed PMC
11
18
40. Liu H, Jin H, Yue X, et al. Comparison of [ C]TZ1964B and [ F]MNI659 for PET imaging brain PDE10A in nonhuman primates.
Pharmacol Res Perspect 2016;4:e00253.
41. Goertsen D, Flytzanis NC, Goeden N, et al. AAV capsid variants with brain-wide transgene expression and decreased liver targeting
after intravenous delivery in mouse and marmoset. Nat Neurosci 2022;25:106-15. DOI PubMed
42. Terstappen GC, Meyer AH, Bell RD, Zhang W. Strategies for delivering therapeutics across the blood-brain barrier. Nat Rev Drug
Discov 2021;20:362-83. DOI PubMed
43. Barres BA. The mystery and magic of glia: a perspective on their roles in health and disease. Neuron 2008;60:430-40. DOI PubMed
44. Allen NJ, Lyons DA. Glia as architects of central nervous system formation and function. Science 2018;362:181-5. DOI PubMed
PMC
45. Stephenson J, Nutma E, van der Valk P, Amor S. Inflammation in CNS neurodegenerative diseases. Immunology 2018;154:204-19.
DOI PubMed PMC
46. Scheiblich H, Trombly M, Ramirez A, Heneka MT. Neuroimmune connections in aging and neurodegenerative diseases. Trends
Immunol 2020;41:300-12. DOI PubMed
47. Ulland TK, Colonna M. TREM2 - a key player in microglial biology and Alzheimer disease. Nat Rev Neurol 2018;14:667-75. DOI
PubMed
48. Poduri A, Gearing M, Rebeck GW, Mirra SS, Tigges J, Hyman BT. Apolipoprotein E4 and beta amyloid in senile plaques and
cerebral blood vessels of aged rhesus monkeys. Am J Pathol 1994;144:1183-7. PubMed PMC
49. Mahley RW, Weisgraber KH, Huang Y. Apolipoprotein E4: a causative factor and therapeutic target in neuropathology, including
Alzheimer’s disease. Proc Natl Acad Sci U S A 2006;103:5644-51. DOI PubMed PMC
50. Herndon JG, Moss MB, Rosene DL, Killiany RJ. Patterns of cognitive decline in aged rhesus monkeys. Behavioural Brain Research
1997;87:25-34. DOI PubMed
51. Frye BM, Craft S, Register TC, et al. Early Alzheimer’s disease-like reductions in gray matter and cognitive function with aging in
nonhuman primates. Alzheimers Dement (N Y) 2022;8:e12284. DOI PubMed PMC
52. Scheltens P, De Strooper B, Kivipelto M, et al. Alzheimer’s disease. Lancet 2021;397:1577-90. DOI PubMed PMC
53. Alzheimer’s disease facts and figures. Alzheimers Dement 2021;17:327-406. DOI PubMed
54. Perrin RJ, Fagan AM, Holtzman DM. Multimodal techniques for diagnosis and prognosis of Alzheimer’s disease. Nature