Page 353 - Read Online

Radhakrishnan et al. Vessel Plus 2019;3:36 I http://dx.doi.org/10.20517/2574-1209.2019.23 Page 3 of 8

Figure 1. endarterectomy

Table 1. Patient demographics in control and study population
Variable CABG + LCAE (n = 87) CABG (n = 75) P value
Age 67 (37-85) 64(43-84) 0.06
Sex M 68, F 19 M 62, F 13 0.55
Diabetes Mellitus 8/87 16/75 0.04
Hypertension 48/87 35/75 0.34
Parsonnet score 8( 0-43) 6.9 (0-27) 0.10
Timing of Surgery
Elective 27 11 0.01
Urgent inpatient 60 62 0.02
Emergency 0 2 0.21
Salvage 2 0 0.49
CABG: coronary artery bypass grafts; LCAE: left coronary artery endarterectomy

As part of our routine clinical practice, all patients undergoing CABG receive dual antiplatelet therapy
(DAPT) post-operatively. Aspirin 300mg is given at 4-6 h post-operatively and 150 mg/day after that which
was recommended to continue lifelong. In addition to aspirin, patients received clopidogrel 300 mg at 4-6 h
post-operatively and 75 mg/day after that, which was recommended to continue for 1-year. In both groups,
DAPT was administered if the bleeding was < 150 mL/h for the first 4 h postoperatively.

Statistical analysis
Statistical significance was designed to test the all or none hypothesis that use of concomitant coronary
endarterectomy will not affect the outcome of Coronary artery bypass grafting. Statistical significance was
obtained by a P-value < 0.05. Nominal data were analyzed using the Fisher test and interval data using
the student t-test. Actuarial survival curves were calculated using the Kaplan Meier survival analysis. All
statistical analysis was done using the GraphPad Prism statistical package.

RESULTS
The patient demographics were similar in both the groups as presented in Table 1, except for the incidence
of Diabetes Mellitus in the CABG group and increased elective surgery numbers in the LCAE group.