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Paraggio et al. Vessel Plus 2019;3:12  I  http://dx.doi.org/10.20517/2574-1209.2018.72                                                 Page 5 of 11


                            A                                B
















                            C                                D
















               Figure 2. “Anchoring balloon” technique example. A: Basal angiographic assessment; B: angiographic evaluation after proximal stent
               implantation; C: GuideLiner delivery with distal anchoring balloon; D: final angiography after three more overlapping stents implantation




               GUIDEWIRES AND MICROCATHETERS: A BAG OF TRICKS
               The toolbox of CTO operators has rapidly increased over the last decade as new tools and equipments
               have been developed. A complete knowledge of such equipment is now essential for every interventional
               cardiologist in order to improve performance in everyday PCI.

               Specialized CTO guidewires are now commonly available in every cathlab as they represent the key tool
               to afford antegrade crossing of CTO lesions. Indeed, antegrade wire escalation is the most commonly
               used technique to cross the lesion throughout the true vessel lumen and involves progressive utilization of
               guidewires with various stiffness and/or penetrating force. Moreover, with the development of global interest
               over CTO procedures, such guidewires have been extensively publicized even in international conventions
               and their characteristics are now familiar to every interventional cardiologist [Table 2]. In everyday
               practice, soft, tapered and polymer-jacketed wires, such as the Fielder family (Asahi Intecc, Japan), could
               be very useful to cross very narrowed lesions, especially in calcified vessels. In this setting, the polymeric
               coating together with the tapered tip of such guidewires may be helpful in navigating a narrow true lumen
               of a tortuous calcified vessel minimizing the risk of causing a dissection. However, routine use of polymer
               jacketed guidewires with higher tip weigh should be avoided in everyday practice. Beyond CTO guidewires,
               a new family of workhorse wires called Sion (Sion, Sion Blue and Sion Black; Asahi Intecc, Japan),
               characterized by a higher direction and torque response, have been developed and have showed such ability
               in retrograde collaterals crossing. Such wires are essentially driven by a new technology called “Composite
               Core”: the parallel placement of a classic wire and a twist wire linked at the distal tip determine a more
               precise transmission of torque rotation. Such characteristics make Sion guidewires very useful in daily PCI
               in every case of difficult distal wire positioning in tortuous and/or calcified vessels and in bifurcation PCI
               when wiring or re-wiring of side branch is difficult due to a narrow angle.
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