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Im et al. Vessel Plus 2018;2:5 Vessel Plus
DOI: 10.20517/2574-1209.2018.07

Original Article Open Access

Adherence to guidelines: primary prevention with
aspirin in 1125 medical check-up participants

Jin Hee Im , Sang Won Han , Seon Yeong Lee , Jong Sam Baik 1
1
1
2
1 Department of Neurology, Sanggye Paik Hospital, Inje University College of Medicine, Seoul 01757, South Korea.
2 Department of Family Medicine, Sanggye Paik Hospital, Inje University College of Medicine, Seoul 01757, South Korea.
Correspondence to: Dr. Jong Sam Baik, Department of Neurology, Sanggye Paik Hospital, Inje University College of Medicine,
761-1 Sanggye 7-dong, Nowon-gu, Seoul 01757, South Korea. E-mail: jsbaik@paik.ac.kr
How to cite this article: Im JH, Han SW, Lee SY, Baik JS. Adherence to guidelines: primary prevention with aspirin in 1125 medical
check-up participants. Vessel Plus 2018;2:5. http://dx.doi.org/10.20517/2574-1209.2018.07
Received: 5 Mar 2018 First Decision: 22 Mar 2018 Revised: 4 Apr 2018 Accepted: 11 Apr 2018 Published: 18 Apr 2018

Science Editor: Aaron S. Dumont Copy Editor: Jun-Yao Li Production Editor: Cai-Hong Wang

Abstract
Aim: The aim of the present study was to assess the 10-year cardiovascular disease (CVD) risk and to apply the current
recommendations on aspirin use for primary prevention in Korean participants undergoing a medical check-up.

Methods: Adults aged 50 to 69 years were eligible for the study if they did not have a history of atherosclerotic CVD
(ASCVD) or stroke. The 10-year CVD risk was calculated using the ASCVD risk estimator (http://tools.acc.org/
ASCVD-Risk-Estimator).

Results: A total of 1125 participants were enrolled in this study. The mean age was 57 years, and 32% of the participants
were women. Based on the 2016 US Preventive Services Task Force recommendations, aspirin was indicated in 266
(23.6%) participants but only 44 (3.9%) participants were taking aspirin regularly. Among these participants, aspirin
was prescribed appropriately in 36% of the participants, suggesting that only 6% of the participants were taking aspirin
appropriately and 3.3% of the participants were taking aspirin inappropriately. Logistic regression analysis showed that
treatment for hypertension was significantly associated with taking aspirin (odds ratio 7.49; 95% confidence interval
3.62-15.49).

Conclusion: Our study suggested that there may be an opportunity for decreasing the rate of CVD as well as the risk for
major bleeds through tailored education on aspirin use.

Keywords: Aspirin, cardiovascular disease, guideline, primary prevention, stroke

© The Author(s) 2018. Open Access This article is licensed under a Creative Commons Attribution 4.0
International License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use,
sharing, adaptation, distribution and reproduction in any medium or format, for any purpose, even commercially, as long
as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license,
and indicate if changes were made.

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