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Vessel Plus 2018;2:31 Vessel Plus
DOI: 10.20517/2574-1209.2018.58

Meeting Abstracts Open Access

Selected meeting abstracts of 2018 healthcare and
cardiology conference

Bangkok, Thailand; September 18-19, 2018; Published: 16 Oct 2018

Correspondence to: Dr. Ahmed Ahmed Fouad Abdelwahab Ahmed, Consultant Cardiac Surgeon, Ain Shams University,
11566 Cairo, Egypt. E-mail: afouad38@yahoo.com

1. Evaluation of the role of ischemia reversal therapy in ischemic heart disease using
SPECT myocardial perfusion imaging: a pilot study

1
Rohit Sane , Rahul Mandole 2

1 Founder, Madhavbaug Cardiac Care Clinics and Hospital, Mumbai 400603, India.
2 Department of R&D, Madhavbaug Cardiac Care Clinics and Hospital, Mumbai 400603, India.

Ischemic heart disease (IHD) incidence has increased in India. Ayurveda, a 3000-year-old Indian traditional
medicine system along with allopathic medicine can provide a solution to improve myocardial perfusion
in stable IHD patients. This pilot study involves ischemia reversal programme (IRP), an Ayurvedic treat-
ment modality to aid IHD patients using SPECT-myocardial perfusion imaging (SPECT-MPI) for assess-
ment of myocardial perfusion in IHD patients. The present open-label study involved fourteen IHD pa-
tients who underwent IRP (21 sittings in total, administered twice per week) in Madhavbaug clinics along
with their standard care therapy. The inclusion criteria were patients with known IHD, age = 40-70 years,
2
BMI > 20 kg/m , and stress test positive for inducible ischemia. SPECT-MPI was performed at enrolment and
post-IRP (12-week follow-up) from December 2016 to September 2017. VO2max and time to onset of isch-
emia after stress test were also recorded. Seattle angina questionnaire (SAQ) was telephonically completed
by research coordinators. Observations from SPECT-MPI test showed a significant difference in summed
stress score (13.5 ± 10.3, baseline vs. 10.7 ± 10.1, post-IRP; P = 0.01) as well as summed difference score (8.9 ±
6.2, baseline vs. 6.2 ± 6.3, post- IRP; P = 0.03) compared from baseline to post-IRP sittings. And we also ob-
served the increase in VO2max levels (12.8 ± 5.7 to 19.4 ± 7.8) and the time to onset of ischemia (370.7 ± 201.1
to 597.8 ± 201.9) was observed. SAQ scores showed significant improvement post-IRP (30.2 ± 3.6 to 32.7± 3.5).
Findings of this study suggest an improvement in myocardial perfusion post-IRP in IHD patients and depict
the positive role of IRP as an add-on to standard care therapy in IHD management.

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