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Kolba et al. Vessel Plus 2023;7:12 Vessel Plus
DOI: 10.20517/2574-1209.2022.61

Original Article Open Access

No mental illness impact on post-aortic valve

replacement patients’ new-onset atrial fibrillation

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Natalie Kolba , Julia Dokko , Samantha Novotny , Sohaib Agha , Ashutosh Yaligar , Jennifer Morrone ,
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Puja B. Parikh , Aurora D. Pryor , Henry J. Tannous , Thomas Bilfinger , A. Laurie Shroyer 2
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Renaissance School of Medicine, Undergraduate Medical Education, Stony Brook University, Stony Brook, NY 11733-8191, USA.
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Department of Surgery, Stony Brook University School of Medicine, Stony Brook, NY 11733-8191, USA.
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Department of Medicine, Stony Brook University School of Medicine, Stony Brook, NY 11733-8191, USA.
Correspondence to: Prof. A. Laurie Shroyer PhD, Department of Surgery, Stony Brook Renaissance School of Medicine, Health
Science Center 19-080, 100 Nicolls Road, Stony Brook, NY 11733-8191, USA. E-mail:
AnnieLaurie.Shroyer@stonybrookmedicine.edu
How to cite this article: Kolba N, Dokko J, Novotny S, Agha S, Yaligar A, Morrone J, Parikh PB, Pryor AD, Tannous HJ, Bilfinger T,
Shroyer AL. No mental illness impact on post-aortic valve replacement patients’ new-onset atrial fibrillation. Vessel Plus
2023;7:12. https://dx.doi.org/10.20517/2574-1209.2022.61
Received: 26 Sep 2022 First Decision: 3 Apr 2023 Revised: 9 May 2023 Accepted: 9 Jun 2023 Published: 30 Jun 2013
Academic Editors: Carlos A. Mestres Frank W. Sellke Copy Editor: Fangling Lan Production Editor: Fangling Lan
Abstract
Aim: The mental illness (MEI) impact upon risk-adjusted first-time aortic valve replacement (AVR) or repeat AVR
(r-AVR) outcomes is unknown. Comparing patients with and without new-onset postoperative atrial fibrillation or
atrial flutter (POAF/AFL), this retrospective cohort investigation evaluated if MEI impacted patients’ risk-adjusted
AVR/r-AVR outcomes.
Methods: Using de-identified New York Statewide Planning and Research Cooperative System (administrative)
database reports, multivariable logistic regression models compared post-procedural POAF/AFL, 30-day
readmission, and composite (i.e., 30-day operative mortality or morbidity) endpoints between MEI and non-MEI
patients.

Results: From 2005-2018, there were 36,947 first-time AVR patients and 242 r-AVR patients; of these, 13.18%
AVR (n = 4,868) and 16.94% r-AVR (n = 41) patients had preprocedural MEI diagnoses. Compared to non-MEI
patients, MEI patients had increased rates of transcatheter vs. surgical procedures and higher pre-procedural risks
including alcoholism, illegal drug use, tobacco product use, suicidal ideation, or other comorbidities (e.g., valvular
disease, atherosclerotic disease, hypertension obesity, and anemia); they were younger, female, and non-
Black/non-Hispanic, and had non-commercial (e.g., government or self-pay) insurance. Contrasted to non-MEI

© The Author(s) 2023. Open Access This article is licensed under a Creative Commons Attribution 4.0
International License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, sharing,
adaptation, distribution and reproduction in any medium or format, for any purpose, even commercially, as
long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and
indicate if changes were made.

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