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               CONCLUSION
               Patients with stroke in rural and remote areas around the world have an unacceptable inequity in access to
               acute treatment compared to their urban counterparts. New approaches are urgently needed to overcome
               this service delivery gap. The concept of an Air-MSU “bringing the stroke treatment to the patient” and
               linked to telemedicine services may be a novel solution to allow diagnosis of stroke patients at the
               emergency site. This is likely to facilitate faster triage and initiation of acute stroke treatment. The mobility
               and flexibility of the Air-MSU concept may present a superior strategy to the more obvious and traditional
               approach of overcoming tyranny of distance by establishing more on-site stroke capable health care
               facilities. The development of novel diagnostic imaging and diagnostic tools may help reduce the cost of
               implementation of an Air-MSU service. While early implementation is more likely in developed countries,
               and further research is needed to understand the optimal technical and clinical settings, lessons learned may
               later become important for developing nations. Also, careful cost benefit analysis for the individual settings
               will be needed, which not only addresses the overall benefits but also the question of availability of
               resources, costs of implementation, and financial sustainability, which are crucial factors for most countries
               worldwide.


               DECLARATIONS
               Authors’ contributions
               Wrote drafts of the manuscript, conceptualized ideas, provided inputs for all aspects of the manuscript
               preparation and of the scientific content and reviewed the manuscript: Walter S, Easton D, Schwarz M,
               Zhao H, Davis SM, Donnan GA
               Conceptualized ideas, edited and critically reviewed and discussed the manuscript: Fassbender K, Gardiner
               FW, Langenberg F, Dos Santos A, Bil C, Fox K, Bishop L, Coote S, Middleton S, Bladin C


               Availability of data and materials
               Not applicable.


               Financial support and sponsorship
               None.


               Conflicts of interest
               All authors declared that there are no conflicts of interest.


               Ethical approval and consent to participate
               Not applicable.


               Consent for publication
               Not applicable.

               Copyright
               © The Author(s) 2021.

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