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Page 4 of 10 Dall’Ara et al. Vessel Plus 2023;7:26 https://dx.doi.org/10.20517/2574-1209.2023.107

Table 1. Baseline characteristics
Overall Fem 1 2
Variable Rad_Stand 114 (51.1) Rad_SGC 37 (16.6) P P
n = 223 72 (32.2)
Age, years 74.8 ± 9.1 74.8 ± 9.1 74.0 ± 9.2 74.7 ± 8.4 0.259 0.700
Male gender 162 (72.6) 47 (65.3) 92 (80.7) 23 (62.2) 0.021 0.021
Hypertension 193 (86.5) 62 (86.1) 99 (86.8) 32 (86.5) 0.990 1.000
Hypercholesterolemia 166 (74.4) 52 (72.2) 88 (77.8) 26 (70.3) 0.613 0.395
Current smoker 80 (35.9) 28 (38.9) 37 (32.5) 15 (40.5) 0.545 0.369
2
BMI > 30 Kg/m 51 (22.9) 17 (23.6) 29 (25.4) 5 (13.5) 0.319 0.131
Diabetes mellitus 97 (43.5) 32 (44.4) 52 (45.6) 13 (35.1) 0.525 0.263
Dialyses 13 (5.8) 7 (9.7) 6 (5.3) 0 (0.0) 0.114 0.337
PAD 78 (35.0) 30 (41.7) 35 (30.7) 13 (35.1) 0.311 0.615
Ejection fraction, % 50 (40-55) 50 (42-55) 50 (45-55) 50 (40-60) 0.416 0.503
Ejection fraction < 30% 14 (6.4) 8 (11.3) 3 (2.7) 3 (8.3) 0.060 0.155
Clinical presentation: 0.101 0.051
- ACS 99 (44.4) 29 (40.3) 58 (50.9) 12 (32.4)
- Stable/staged 124 (55.6) 43 (59.7) 56 (49.1) 25 (67.6)
Antithrombotic therapy:
- Vit.K ant./DOAC 25 (11.2) 12 (16.7) 9 (7.9) 4 (10.8) 0.181 0.522
- DAPT pretreatment 68 (30.5) 22 (30.6) 32 (28.1) 14 (37.8) 0.533 0.262

Categorical variables are shown as number (percentage); continuous variables as median (interquartile range) or mean value (±standard
deviation). ACS: Acute coronary syndrome; BMI: body mass index; DAPT: double antiplatelet therapy; DOAC: direct oral anticoagulant; Fem:
femoral access; PAD: peripheral artery disease; Rad_SGC: radial sheathless guiding catheter access; Rad_Stand: radial standard access; Vit.K ant:
1 2
vitamin K antagonist; P : comparison between the three groups; P : comparison between the two radial groups.

Figure 1. A case of RA PCI using an SGC. Panels (A and B) show diagnostic angiography in cranial and caudal view, respectively; (C)
IVUS evaluation of the minimal lumen area of the calcific lesion; (D) left anterior descending artery ostial calcific lesion; (E) longitudinal
IVUS view; (F) radio-opacities on both side of the lumen on still cardiac fluoroscopy images; (G) ongoing rotational atherectomy; (H)
and (I) final angiography.

Procedural time was longer in the case of femoral access [Table 2]. Only 27.4% of the procedures were
performed with a 6 Fr guiding catheter. We did not perceive any differences between groups in terms of