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Favre et al. Plast Aesthet Res 2020;7:71 I http://dx.doi.org/10.20517/2347-9264.2020.149 Page 7 of 12

Figure 5. Injection sites for upper lip rhytids into the lip elevator muscles

Figure 6. Injection sites for melomental folds into the depressor anguli oris muscle

Chin
One of the most common areas of the face frequently injected with BoNT for aesthetic reasons is the
chin, with the main muscle of injection being the mentalis muscle. The mentalis has two muscle bellies
that originate from the mentum and insert onto the chin soft tissue under the lip. Its function is to elevate
and protrude the lower lip while wrinkling the skin of the chin, often producing the emotions of doubt or
[13]
“pouting” . Injections to improve the wrinkling of the chin and aesthetic appearance of this area can be
performed with a single injection in the midline of the chin with 5 units of ONA or bilaterally in each of
[3]
the muscle bellies with 2 units of ONA per injection [Figure 7]. Patients are often satisfied with the results
of decreased wrinkling in the mental area after injection.

OTHER USES OF BONT
Masseteric hypertrophy
The masseter muscle originates from the inferior border of the zygomatic arch and inserts onto the angle
and ramus of the mandible, functioning to elevate and protract the mandible to close the jaw. Hypertrophy