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Ziai et al. Plast Aesthet Res 2020;7:53  I  http://dx.doi.org/10.20517/2347-9264.2020.151                                          Page 9 of 13
























               Figure 5. Hyaluronic acid injection to the superior sulcus. The needle or cannula should enter along the superior orbital rim at a 30°
               angle. After the needle has reached the bone, it should be slightly withdrawn to the preperiosteal space to inject into the suborbicularis
               plane. Adapted with permission from Looi et al. [31]


                                  A













                                  B
















               Figure 6. Combination of hyaluronic acid injection into the glabellar rhytids with chemodenervation: (A) pre-injection; and (B) two
               months after the glabellar injection of 0.1 mL on the right and 0.2 mL on the left of Restylane-L


               with a low G’ are typically required to efface these lines. The senior author prefers using a 30-gauge
               needle with bevel down for these injections. The filler should be injected in the subcutaneous plane and
               immediately massaged after injection to achieve an even contour and avoid early-onset nodules or visibility
               [Figure 6].

               COMPLICATIONS
               Vascular occlusion
               Vascular occlusion is one of the most devastating complications of filler injections. In the periocular area,
               this can result in intra-arterial embolization or vascular compression and subsequent vision loss or skin
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