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Lane et al. Plast Aesthet Res 2020;7:51  I  http://dx.doi.org/10.20517/2347-9264.2020.106                                       Page 5 of 15

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               Figure 2. Radial forearm free flap (RFFF) [31] . A-B: tube-in-a-tube. The flap is then folded in to make two tubes, with epithelium lining the
               urethra as well as the surface of the phallus. There is a resultant large donor site defect requiring skin grafting. The RFFF is based upon
               the radial artery with the original flap dimensions of 10 cm × 11-12 cm. The length of this flap is determined in part by the length of the
               forearm, which will limit the length of the reconstructed phallus. Photos courtesy of Dr. Jens Berli

               PHALLOPLASTY
               The large cutaneous surface area of the male phallus dictates the use of a large cutaneous flap for phallic
               construction. In the past, random-pattern cutaneous flaps were most commonly used, but axial pedicled or
               microvascular free flaps dominate at present [29-31] . The free radial forearm flap (RFFF) and the anterolateral
               thigh pedicled or free flap (ALT) are, by a considerable margin, the most common donor site choices
               currently. The latissimus dorsi (LD) myocutaneous flap [32,33]  and the superficial circumflex iliac artery flap
               (SCIP) [34,35]  are used at select centers. The free fibula osteocutaneous flap [35-37]  and the lower abdominal
               pedicled flap [29,38]  are used less frequently. To add to this heterogeneity, the method of penile urethra
               construction will influence flap choice and, at times, entail “composite phalloplasty” which is the use of two
               separate flaps: one for the phallus itself and a second flap for the pars pendulans urethra.

               At present, the most commonly employed flap for phallic construction in transmasculine patients is the
                                                   [28]
               RFFF, first reported by Chang and Hwang  in 1984 [Figure 2]. Advantages of the RFFF are: (1) extremely
                                                        [39]
               reliable vascular and peripheral neural anatomy ; (2) the forearm is thin and pliable in most individuals,
               allowing for simultaneous creation of the pars pendulans urethra via the “tube-in-a-tube” technique [28,40] ;
               and (3) the RFFF having the highest innervation density of all the available flaps, providing the best
               potential for cutaneous reinnervation, and the ulnar, volar surface of the forearm being hair-free in many
               individuals, lessening or sometimes even obviating the need for hair removal prior to phalloplasty. In
               addition, the RFFF donor site results in no significant functional disturbance of the arm and hand for the
                                     [41]
               large majority of patients . The primary disadvantages of the RFFF are the large donor defect in forearm
                                                                                                       [42]
               that must be skin grafted, occasional complications including edema in the hand or sensory neuromas ,
               and, if the patient’s forearm is short, a limitation on phallic length [Figure 2]. Despite strategies to
                                        [43]
               reduce donor site deformity , some patients refuse the RFFF as they consider the forearm scar to be
                          [44]
               stigmatizing . Regardless, most surgeons performing gender confirming phalloplasties consider the RFFF
               to be the best flap donor site at the present time.
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