Page 472 - Read Online

Page 16 of 20 Citterio et al. Plast Aesthet Res 2020;7:41 I http://dx.doi.org/10.20517/2347-9264.2020.29

regeneration are unsatisfactory, for instance in furcation defects. In this field, the development of cell-based
therapy could provide its greatest benefit in the future.

DECLARATIONS
Authors’ contributions
Performed data acquisition, as well as provided administrative, technical, and material support: Citterio F,
Gualini G, Fierravanti L
Supervision: Aimetti M
Write the final review and tables: Citterio F, Gualini G, Fierravanti L

Availability of data and materials
Not applicable.

Financial support and sponsorship
None.

Conflicts of interest
All authors declared that there are no conflicts of interest.

Ethical approval and consent to participate
Not applicable.

Consent for publication
Not applicable.

Copyright
© The Author(s) 2020.

REFERENCES
1. Aimetti M, Perotto S, Castiglione A, Mariani GM, Ferrarotti F, et al. Prevalence of periodontitis in an adult population from an urban area
in North Italy: findings from a cross-sectional population-based epidemiological survey. J Clin Periodontol 2015;42:622-31.
2. Chapple I. Iain Chapple: ‘as a Clinician, You Assume That People Know What Periodontitis Is’. Vol 215. Br Dent J 2013:431-4.
3. Ide M, Linden GJ. Periodontitis, cardiovascular disease and pregnancy outcome--focal infection revisited? Br Dent J 2014;217:467-74.
4. Lalla E, Papapanou PN. Diabetes mellitus and periodontitis: a tale of two common interrelated diseases. Nat Rev Endocrinol 2011;7:738-48.
5. Araújo VMA, Melo IM, Lima V. Relationship between periodontitis and rheumatoid arthritis: review of the literature. Mediators Inflamm
2015;2015:259074.
6. Loos BG. Systemic effects of periodontitis. Int J Dent Hyg 2006;4:34-52.
7. Chapple ILC. Time to take periodontitis seriously. BMJ 2014;348:g2645.
8. Chapple IL, Van der Weijden F, Doerfer C, Herrera D, Shapira L, et al. Primary prevention of periodontitis: managing gingivitis. J Clin
Periodontol 2015;42:S71-6.
9. Petersen PE, Ogawa H. The global burden of periodontal disease: towards integration with chronic disease prevention and control.
Periodontol 2000 2012;60:15-39.
10. Pihlstrom BL, Michalowicz BS, Johnson NW. Periodontal diseases. Lancet 2005;366:1809-20.
11. Cortellini P, Buti J, Pini Prato G, Tonetti MS. Periodontal regeneration compared with access flap surgery in human intra-bony defects 20-
year follow-up of a randomized clinical trial: tooth retention, periodontitis recurrence and costs. J Clin Periodontol 2017;44:58-66.
12. Suvan J, Leira Y, Moreno F, Graziani F, Derks J, et al. Subgingival instrumentation for treatment of periodontitis. a systematic review. J
Clin Periodontol 2019; doi: 10.1111/jcpe.13245.
13. Sanz-Sánchez I, Montero E, Citterio F, Romano F, Molina A, et al. Efficacy of access flap procedures compared to subgingival
debridement in the treatment of periodontitis. A systematic review and meta-analysis. J Clin Periodontol 2020; doi: 10.1111/jcpe.13259.
14. Trombelli L, FrancESCshetti G, Farina R. Effect of professional mechanical plaque removal performed on a long-term, routine basis in
the secondary prevention of periodontitis: a systematic review. J Clin Periodontol 2015;42:S221-36.
15. Matuliene G, Pjetursson BE, Salvi GE, Schmidlin K, Brägger U, et al. Influence of residual pockets on progression of periodontitis and
tooth loss: results after 11 years of maintenance. J Clin Periodontol 2008;35:685-95.