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in solution that slowly release their oxygen gas into the solution in which they are formed, providing a
revolutionary new modality for tissue oxygenation. Strong data have demonstrated improved wound
oxygenation, transplant survival and preservation times. This may have major implications for plastic
surgery: oxygenation of lipoaspirate and improved fat graft survival [117] .

CONCLUSION
Fat and stem cell technology offer tremendous clinical applications in plastic surgery. We still need to
continue to work on the science of this technology. Only by understanding the molecular and tissue
interactions will we be able to modify and utilize this technology to its full advantage.

DECLARATIONS
Authors’ contributions
Dr Evans and Widgerow contribution was equal

Availability of data and materials
Not applicable.

Financial support and sponsorship
None.

Conflicts of interest
Both authors declared that there are no conflicts of interest.

Ethical approval and consent to participate
Not applicable.

Consent for publication
Not applicable.

Copyright
© The Author(s) 2020.

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