Page 113 - Read Online
P. 113
Wiedner et al. Plast Aesthet Res 2020;7:10 I http://dx.doi.org/10.20517/2347-9264.2019.51 Page 9 of 10
to a paradigm shift in the treatment of lipedema. While conservative therapy may reduce symptoms
temporarily, liposuction is able to remove the pathologic adipose tissue, which may result in a sustainable
symptom relief. Liposuction is an effective surgical method and should be individually considered for
patients suffering from lipedema. Weight management is a key component of successful treatment whether
conservative or surgical.
DECLARATIONS
Authors’ contributions
Made substantial contributions to conception and design of the article: Wiedner M, Aghajanzadeh D,
Richter DF
Availability of data and materials
Not applicable.
Financial support and sponsorship
None.
Conflicts of interest
All authors declared that there are no conflicts of interest.
Ethical approval and consent to participate
Not applicable.
Consent for publication
Written informed consent for publication of images was obtained from the patients shown on the images.
Copyright
© The Author(s) 2020.
REFERENCES
1. Allen EV, Hines EA. Lipedema of the legs: a syndrome characterised by fat legs and orthostatic edema. Proc Staff Meet Mayo Clin
1940;15:184-7.
2. Herpertz U. Krankheitsspektrum des lipödems an einer lymphologischen fachklinik- erscheinungsformen, mischbilder und
behandlungsmöglichkeiten. Vasomed 1997;5:301-3.
3. Meier-Vollrath I, Schneider W, Schmeller W. Lipödem: Verbesserte Lebensqualität durch Therapiekombination. Deutsches Ärzteblatt
2005;15:A1061-7.
4. Lulay G. Lymphologische akutklinik- ein neues versorgungskonzept. Lymphol Forsch Praxis 2010;14:90-5.
5. Child AH, Gordon KD, Sharpe P, Brice G, Ostergaard P, et al. Lipedema: an inherited condition. Am J Med Genet A 2010;152A:970-6.
6. Langendoen SI, Habbema L, Nijsten TE, Neumann HAM. Lipoedema: from clinical presentation to therapy. A review of the literature. Br
J Dermatol 2009;161:980-6.
7. Weissleder H, Schuchhardt C, et al. Lymphedema. Diagnosis and therapy. WVP. Wirtschafts- und Praxisverlag; 2007.
8. Szél E, Kemény L, Groma G, Szolnoky G. Pathophysiological dilemmas of lipedema. Med Hypotheses 2014;83:599-606.
9. Mayes JS, Watson GH. Direct effects of sex steroid hormones on adipose tissues and obesity. Obes Rev 2004;5:197-216.
10. Herbst K, Mirkovskaya L, Bharhagava A, Chava Y, Te CHT. Lipedema fat and signs and symptoms of illness, increase with advancing
stage. Arch Med 2015;7:10.
11. Bauer AT, Lukowicz D, Lossagk K, Hopfner U, Kirsch M, et al. Adipose stem cells from lipedema and control adipose tissue respond
differently to adipogenic stimulation in vitro. Plast Reconstr Surg 2019;144:623-32.
12. Brauer W, Cornely M, Faerber G, Lulay GR., Miller A, et al. Lipödem S1 Leitlinie. Available from: https://www.phlebology.de/aerzte/
wissen/leitlinien/ [Last accessed on 16 Feb 2020] (in German)
13. Van Geest AJ, Esten SCAM, Cambier J-PRA, Gielen EGJ, Kessels A, et al. Lymphatic disturbances in lipoedema. Phlebologie
2003;32:138-42.
14. Wold LE, Hines Jr EA, Allen EV. Lipedema of the legs: a syndrome characterized by fat legs and edema. Ann Intern Med 1951;34:1243-