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Page 6 of 11 Friedman et al. Plast Aesthet Res 2022;9:58 https://dx.doi.org/10.20517/2347-9264.2022.77

Table 2. Measurements of limb volume and hours spent in compression therapy at the time of preoperative evaluation and 12
months post-VLNT in patients with fat- or fluid-dominant lymphedema phenotypes
Baseline 12-month visit
Relative volume change, %
Fluid dominant (n = 8)
Median, Q1-Q3 - -2% (-4%-1.6%)
Fat dominant (n = 9)
Median, Q1-Q3 - 2.6% (-0.4%-5.6%)
Compression therapy, hours
Fluid dominant (n = 6)
Median, Q1-Q3 46.5 (0.8-106) 3.5 (0-49.8)
Fat dominant (n = 9)
Median, Q1-Q3 168 (168-168) 168 (168-168)
L-Dex score
Fluid dominant (n = 7)
Median, Q1-Q3 15.8 (11.6-36) 30.6 (10.3-34.8)
Fat dominant (n = 8)
Median, Q1-Q3 17 (3.6-25.6) 16.8 (8.4-25.4)

VLNT: Vascularized lymph node transplantation.

Table 3. LYMQOL Domain Scores at the time of preoperative evaluation and 12 months post-VLNT and at 12 months following VLNT
Baseline 12-month visit
Fluid dominant (n = 4)
Appearance
Median, Q1-Q3 2.6 (1.9-3.3) 1.8 (1.6-2.1)
Functional
Median, Q1-Q3 1.9 (1.6-3.2) 1.4 (1.4-1.8)
Mood
Median, Q1-Q3 2.3 (1.6-3.2) 1.7 (1.6-1.9)
Symptoms
Median, Q1-Q3 2.7 (2.3-2.9) 2.3 (1.8-2.7)
Fat dominant (n = 5)
Appearance
Median, Q1-Q3 1.4 (1.4-2.4) 1.4 (1.2-1.6)
Functional
Median, Q1-Q3 1.3 (1.2-1.6) 1.2 (1.1-1.3)
Mood
Median, Q1-Q3 1.7 (1.7-1.8) 1.2 (1.0-1.2)
Symptoms
Median, Q1-Q3 2.0 (1.8-2.2) 1.8 (1.3-2.0)

LYMQOL: Lymphedema quality-of-life; VLNT: vascularized lymph node transplantation.

Overall, the fat-dominant group (n = 9) demonstrated a limb volume change of 3% (0%-6%) without a
change in the overall hours spent in compression therapy. L-Dex scores remained constant at 17 (4-26)
preoperatively and 17 (9-25) at twelve months, and an improvement in all subdomains of LYMQOL was
noted, except for the appearance subdomain, which remained unchanged. One of the nine patients in this
group was able to discontinue compression therapy entirely at twelve months. Of the eight patients in this