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Figure 3. Illustration of the TMR surgical approach. Tibial nerve neuroma is resected, followed by denervation of the medial head of the
gastrocnemius muscle motor nerve. Subsequent anastomosis of the tibial nerve to the medial gastrocnemius muscle. Illustrated by
Seitz AJ. TMR: Targeted muscle reinnervation.
Figure 4. Sciatic nerve neuroma resection (left) with differentiation of 4 fascicles. TMR involving fascicles of the sciatic nerve (right)
with an anastomotic connection to adjacent muscle neuron entry into muscle. Photo credit to Dr. Poore SO. TMR: Targeted muscle
reinnervation.
comprehensive approach to the treatment and prevention of neuroma formation, further and more
longitudinal investigations both at the preclinical and clinical levels must be conducted to illustrate its
