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Page 4 of 9              Kondra et al. Plast Aesthet Res 2022;9:36  https://dx.doi.org/10.20517/2347-9264.2021.121

               Table 1. Patient demographics
                                                                            n (%)
                Total number of patients                                      68
                Mean age (years)                                            39.4 ± 16.2
                            2
                Average BMI (kg/m )                                         27.8 ± 5.3
                  Obese (BMI > 30)                                          18 (26.1%)
                  Not obese (BMI < 30)                                      50 (72.5%)
                Sex
                  Male                                                      63 (92.6%)
                  Female                                                    5 (7.4%)
                Comorbidities
                  ≥ 1 comorbidity                                           44 (64.7%)
                  Tobacco                                                   36 (52.9%)
                  Illicit drug use                                          19 (27.9%)
                  Hypertension                                              17 (25.0%)
                  Diabetes mellitus                                         11 (16.2%)
                  Coronary artery disease                                   3 (4.4%)

               BMI: Body mass index.

               In certain cases, the soleus flap was combined with the medial gastrocnemius flap (n = 3), lateral
               gastrocnemius flap (n = 1), vastus lateralis flap (n = 1), and anterolateral thigh flap (n = 1). Skin grafts were
               employed in 67 patients (98.5%). Of note, eight patients (11.8%) suffered from arterial injuries.


               Complications & long-term functional outcomes
               Regarding postoperative complications, twelve patients (17.6%) suffered hardware infections (n = 2) and/or
               osteomyelitis (n = 11) [Table 3]. Among these twelve patients, ten smoked tobacco, six endorsed illicit
               substance use, four had hypertension, two had diabetes mellitus, and one had obstructive sleep apnea. One
               patient with osteomyelitis required a below-the-knee amputation (BKA); notably, this patient suffered a GA
               IIIB injury. Of these 12 patients, there were four concurrent upper extremity fractures and two concurrent
               contralateral lower extremity fractures (n = 4). No statistical significance was found between high severity
               fractures (GA type IIIA-C) and postoperative infection rate. Similarly, no significance was identified
               between diabetes mellitus or > 1 comorbidity and infectious complications.


               Six patients (8.8%) required flap revision and two (2.9%) experienced partial flap loss [Table 3]; notably, six
               of these patients smoked tobacco. Three of the patients who needed flap revision developed osteomyelitis,
               one of which also had a hardware infection. Of the eight patients who suffered arterial injuries, two required
               flap revisions, and one necessitated an above-the-knee amputation (AKA); of note, the latter patient
               suffered a GA IIIC injury. There was 100% flap survival at the most recent clinic follow-up.

               The mean follow-up time from discharge date to latest follow-up with the PRS team was 3.7 months (SD:
               6.8). Of the patients with documented follow-up, 35.3% of patients (n = 24) were independently ambulatory
               after an average of 7.5 months (SD: 7.2) [Figure 1]. Twenty-four patients used a walking assistance device
               (walker or cane) at the most recent follow-up, and twenty patients were wheelchair-dependent [Table 3].


               DISCUSSION
               An interesting trend identified in our review was 84% of soleus flaps were placed prior to 2016, with all
               patients who received soleus flaps for isolated proximal-third leg injuries occurring prior to 2016. With the
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