Page 34 - Read Online
P. 34

filling of pectus excavatum or other malformations of the   4.   Requena L, Requena C, Christensen L, Zimmermann US, Kutzner H, Cerroni
           skeleton. Complications secondary to this filler include   L. Adverse  reactions  to  injectable  soft  tissue  fillers.  J Am Acad  Dermatol
           edema, bruising, nodules, and infections, but no granulomas   5.   2011;64:1-34.
                                                                  Christensen L, Breiting V, Janssen M, Vuust J, Hogdall E. Adverse reactions to
           have been described. Histopathologically, this filler appears   injectable soft tissue permanent fillers. Aesthetic Plast Surg 2005;29:34-48.
           as basophilic amorphous material with granular appearance   6.   De Boulle K. Management of complications after implantation of fillers. J
           surrounded  by sparse numbers of epithelioid histiocytes,   7.   Cosmet Dermatol 2004;3:2-15.
                                                                  Bertossi D, Sbarbati A, Cerini R, Barillari M, Favero V, Picozzi V, Ruzzenente O,
           foreign body multinucleated giant cells, neutrophils, and   Salvagno G, Guidi GC, Nocini P. Hyaluronic acid: in vitro and in vivo analysis,
           red cells. [106-110]                                   biochemical properties  and  histological  and  morphological  evaluation  of
                                                                  injected filler. Eur J Dermatol 2013;23:449-55.
           Polyvinylhdydroxide microspheres                    8.   Wang F, Garza LA, Kang S, Varani J, Orringer JS, Fisher GJ, Voorhees JJ. In
                                                                  vivo stimulation of a de novo collagen production caused by cross-linked
           suspended in polyacrylamide gel                        hyaluronic acid dermal filler injections in photodamaged human skin. Arch
           This  is  a permanent  filler composed of composed of a   Dermatol 2007;143:155-63.
           suspension of 6 polyvinylhydroxide microspheres suspended   9.   Turlier V, Delalleau A, Casas C, Rouquier A, Bianchi P, Alvarez S, Josse G,
                                                                  Briant A, Dahan S, Saint-Martory C, Theunis J, Bensafi-Benaouda A, Degouy
           in 2.5% polyacrylamide gel (Evolution; ProCytech SA),   A, Schmitt  AM, Redoulès D.  Association  between collagen production
           and has been used mostly for lip augmentation. This is a   and mechanical stretching in dermal extracellular matrix: in vivo effect of
           rarely used filler, and there are not descriptions of adverse   cross-linked hyaluronic acid filler. A randomised, placebo-controlled study. J
                                                                  Dermatol Sci 2013;69:187-94.
           reactions to this filler, other that the observation made by   10.  Watson W, Kaye RL, Klein A, Stegman S. Collagen: a clinical overview. Cutis
           Lemperle et al.  who, in their comparative paper on fillers,   1983;31:543-6.
                       [49]
           injected Evolution (and later excised it from the first author’s   11.  Klein AW,  Rish  DC.  Dermatology:  bovine injectable collagen.  West  J Med
           forearm) and found the filler to give little local reaction and   1985;143:231.
           diminish slowly over 9 months. [4]                  12.  Knapp  TR, Kaplan EN, Daniels JR. Injectable collagen  for  soft  tissue
                                                                  augmentation. Plast Reconstr Surg 1977;60:389-405.
                                                               13.  Stegman SJ, Chu S, Bensch K, Amstrong R. A light and electron microscopic
           CONCLUSION                                             evaluation of Zyderm collagen and Zyplast implants in aging human facial
                                                                  skin: a pilot study. Arch Dermatol 1987;123:1644-9.
                                                               14.  Douglas RS, Donsoff I, Cook T, Shorr N. Collagen fillers in facial aesthetic
           Although dermal fillers have been used for decades  in   surgery. Facial Plast Surg 2004;20:117-23.
           aesthetic medicine, the ideal filler is still missing, because all   15.  Mullins RJ,  Richards  C, Walker T. Allergic reaction  to  oral,  surgical  and
           of them known today may cause adverse reactions. Patients’   topical bovine collagen. Anaphylactic risk for surgeons. Aust N Z J Ophthalmol
                                                                  1996;24:257-60.
           safety is hampered by nonlicensed products and users.   16.  Siegle RJ, McCoy JP, Schade  W, Swanson  NA. Intradermal  implantation
           These side effects are tend to be less severe after injection   of  bovine collagen. humoral  immune responses  associated  with clinical
           with non-permanent or semi-permanant biodegradable skin   reactions. Arch Dermatol 1984;120:183-7.
           fillers, which will mostly disappear spontaneously within a   17.  Sclafani A, Romo T, Jacono AA, McCormick SA, Cocker R,Parker A. Evaluation
           few months. Unfortunately, however, after injection with   of  acellular dermal  graft  in sheet  (Alloderm) and  injectable (micronized
                                                                  Alloderm) forms  for soft  tissue augmentation: clinical  observations  and
           slowly or nonbiodegradable permanant fillers, sever adverse   histologic findings. Arch Facial Plast Surg 2000;2:130-6.
           reactions may appear and need active treatment. Follow-up   18.  Fagien  S.  Facial  soft-tissue  augmentation  with injectable autologous  and
           of patients by trained physicians is necessary to reduce risks   allogenic human tissue collagen matrix (autologen and dermalogen). Plast
                                                                  Reconstr Surg 2000;105:362-73.
           and initiate early treatment in case of complications. Careful   19.  Moody BR, Sengelmann RD. Self-limited adverse reaction to human-derived
           selection of patients  and particular selection of products,   collagen injectable product. Dermatol Surg 2000;26:936-8.
           matching particular needs, and skilled injector is the best way   20.  Wise JB, Greco T. Injectable treatments for the aging face. Facial Plast Surg
           to perform safe three-dimensional rejuvenation and achieve   2006;22:140-6.
           high patient’s satisfaction. In the future, individualized,   21.  Lupo MP. Hyaluronic acid fillers in facial rejuvenation. Semin Cutan Med Surg
                                                                  2006;25:122-6.
           specifically tailored  filler  with  long-lasting  effect  but  with   22.  Termeer C, Benedix F, Sleeman J, Fieber C, Voith U, Ahrens T, Miyake K,
           fewer complications might become available.            Freudenberg M, Galanos C, Simon JC. Oligosaccharides  of hyaluronan
                                                                  activate dendritic cells via toll-like receptor 4. J Exp Med 2002;195:99-111.
                                                               23.  Mansouri Y,  Goldenberg  G.  Update  on  hyaluronic  acid  fillers  for  facial
           Financial support and sponsorship                      rejuvenation. Cutis 2015;96:85-8.
           Nil.                                                24.  Turlier V, Delalleau A, Casas C, Rouquier A, Bianchi P, Alvarez S, Josse G,
                                                                  Briant A, Dahan S, Saint-Martory C, Theunis J, Bensafi-Benaouda A, Degouy
           Conflicts of interest                                  A, Schmitt  AM, Redoulès D.  Association  between collagen production
                                                                  and mechanical stretching in dermal extracellular matrix: in vivo effect of
           There are no conflicts of interest.                    cross-linked hyaluronic acid filler. A randomised, placebo-controlled study. J
                                                                  Dermatol Sci 2013;69:187-94.
           REFERENCES                                          25.  Quan T, Wang F, Shao Y, Rittié L, Xia W, Orringer JS, Voorhees JJ, Fisher GJ.
                                                                  Enhancing structural support of the dermal microenvironment activates
                                                                  fibroblasts, endothelial cells, and keratinocytes in aged human skin in vivo. J
           1.   Pak CS, Lee J, Lee H, Jeong J, Kim EH, Jeong J, Choi H, Kim B, Oh S, Kim I, Heo   Invest Dermatol 2013;133:658-67.
              CY. A phase III, randomized, double-blind, matched-pairs, active-controlled   26.  Duranti F, Salti G, Bovani B, Calandra M, Rosati ML. Injectable hyaluronic acid
              clinical trial and preclinical animal study to compare the durability, efficacy   gel for soft tissue augmentation. A clinical and histological study. Dermatol
              and  safety  between  polynucleotide  filler  and  hyaluronic  acid  filler  in  the   Surg 1998;24:1317-25.
              correction of crow's feet: a new concept of regenerative filler. J Korean Med   27.  Narins RS, Brandt F, Leyden J, Lorenc ZP, Rubin M, Smith S. A randomized,
              Sci 2014;29 Suppl 3:S201-9.                         double-blind,  multicenter  comparison  of  the  efficacy  and  tolerability  of
           2.   2014  Complete  Plastic  Surgery  Statistic  Report.  Ameircan  Society  of   Restylane versus Zyplast for the correction of nasolabial folds. Dermatol Surg
              Plastic Surgeons. Available from: http://www.plasticsurgery.org/news/plastic-  2003;29:588-95.
              surgery-statistics/2014-plastic-surgery-statistics.html.   28.  Palm MD. Filler frontier: what's new and heading West to the US market.
           3.   Carruthers J, Carruthers A, Humphrey S. Introduction to fillers. Plast Reconstr   Semin Cutan Med Surg 2014;33:157-63.
              Surg 2015;136 Suppl 5:S120-31.                   29.  Brandt FS, Cazzaniga A. Hyaluronic acid gel fillers in the management of facial
           Plast Aesthet Res || Vol 3 || Mar 23, 2016                                                          97
   29   30   31   32   33   34   35   36   37   38   39