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Deldar et al. Plast Aesthet Res 2022;9:13                                   Plastic and
               DOI: 10.20517/2347-9264.2021.100
                                                                                Aesthetic Research




               Review                                                                        Open Access



               Soft tissue coverage of lower extremity defects:
               pearls and pitfalls in the chronic wound population


                            1,2
                                           2
                                                                 1
               Romina Deldar , Chamilka Merle , Christopher E. Attinger , Karen K. Evans 1
               1
                Department of Plastic and Reconstructive Surgery, MedStar Georgetown University Hospital, Washington, DC 20007, USA.
               2
                Department of General Surgery, MedStar Georgetown University Hospital, Washington, DC 20007, USA.
               Correspondence to: Dr. Karen K. Evans, Department of Plastic and Reconstructive Surgery, MedStar Georgetown University
               Hospital, 3800 Reservoir Road, NW, Washington, DC 20007, USA. E-mail: karen.k.evans@medstar.net,
               prsgeorgetownresearch@gmail.com
               How to cite this article: Deldar R, Merle C, Attinger CE, Evans KK. Soft tissue coverage of lower extremity defects: pearls and
               pitfalls in the chronic wound population. Plast Aesthet Res 2022;9:13. https://dx.doi.org/10.20517/2347-9264.2021.100

               Received: 7 Sep 2021  First Decision: 11 Oct 2021  Revised: 19 Oct 2021  Accepted: 29 Dec 2021  Published: 8 Feb 2022

               Academic Editors: Matthew L Iorio, Marten Basta  Copy Editor: Xi-Jun Chen  Production Editor: Xi-Jun Chen

               Abstract
               The incidence of chronic lower extremity (LE) wounds continues to increase. Lower limb amputations are
               associated with increased cardiovascular exertion, further decline in functional ability, and higher mortality rates.
               As such, there has been a shift towards limb salvage modalities. These include local debridement with advanced
               wound care, revascularization, bony reconstruction, and soft tissue reconstruction. Perioperative planning for soft
               tissue reconstruction requires careful consideration of several factors, including patient comorbidities, wound size
               and location, exposed underlying structures, and in the case of possible free flap, patency of donor and recipient
               vessels. This article reviews the perioperative factors that should be considered in preparation for successful soft
               tissue reconstruction of the LE.

               Keywords: Free tissue transfer, chronic wounds, lower extremity, reconstruction




               INTRODUCTION
               Chronic wounds of the lower extremity (LE) can be defined as wounds that fail to heal within three months
               of onset. LE wounds are a relatively common condition, affecting 1% of the adult population and 3.6% of
               people older than age 65 . This incidence continues to rise as a result of an aging population and increased
                                    [1-3]
               atherosclerotic risk factors such as smoking, obesity, and diabetes mellitus (DM) . Diabetic foot ulcers
                                                                                      [1]




                           © The Author(s) 2022. Open Access This article is licensed under a Creative Commons Attribution 4.0
                           International License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, sharing,
                           adaptation, distribution and reproduction in any medium or format, for any purpose, even commercially, as
               long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and
               indicate if changes were made.

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