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Bolletta et al. Plast Aesthet Res 2019;6:22  I  http://dx.doi.org/10.20517/2347-9264.2019.22                                        Page 5 of 14

               Cutaneous and fasciocutaneous flaps
               Compared to muscle flaps, fasciocutaneous flaps allow supple and thin coverage with ideal surfacing,
               without needing skin grafting. They are also better re-elevated in case of secondary surgeries [17,56,57] .
               Due to the many different perforator flaps described, it is often possible to choose a flap with suitable
               characteristics without needing to change the patient’s position, and often allowing a two-team approach
               in order to reduce operative time. If the deep fascial layer is not needed for reconstructive purposes,
               cutaneous flaps can be elevated above it, including suprafascial components nourished by the perforator
               vessel. Preserving the deep fascia reduces donor site morbidity and chances of muscle herniation. It also
               allows harvesting thinner and more pliable flaps, which can be designed in order to better match the
               characteristics of the defect. Sensory nerves can be included for reinnervation and superficial veins to
                                        [67]
               increase the venous outflow . The flap can be thinned during or immediately after harvesting, hence
                                                                                [68]
               maximizing aesthetic results with a reduced need for surgical revisions . Obviously, the perforator
               dissection of these flaps is technically demanding and it may result in small caliber vessels anastomosis,
               requiring high surgical skills and knowledge of vascular anatomy [69,70] . The characteristics of these flaps
               have increased their use as first option in difficult upper limb reconstructions, where it is extremely
               important to achieve optimal coverage and early rehabilitation.

                         [51]
               Wang et al.  in 2017 reviewed the evidence for application of different important perforator flaps in upper
               extremity reconstruction, such as the anterolateral thigh (ALT), superficial circumflex iliac perforator
               (SCIP), deep inferior epigastric perforator (DIEP) and superficial inferior epigastric artery (SIEA) flaps.
               The ALT resulted in being the most versatile flap, due to the possibility of harvesting it thicker or thinner,
               therefore functional both in larger defects of the proximal arm and distally, where a thin and supple flap is
               needed. The SCIP flap finds its indication in the hand and wrist area [Figure 1] whereas the DIEP and SIEA
               flaps are better suited for the proximal arm. Many authors have reported the use of free fasciocutaneous
               flaps in the lower extremity, even in complicated cases with open fractures, chronic osteomyelitis, diabetic
               complications and limb salvage [56,57,71-75] . The ALT is the flap of choice in many cases, especially in open
               traumatic wounds, with fractures of the tibia, ankle and foot [57,58,72] . It can be utilized with a portion of the
                                                                                   [5]
                                                                 [76]
               fascia lata to reconstruct tendons as well (i.e., the Achilles) . Abdelfattah et al.  evaluated free perforator
               flaps, other than ALT, for the reconstruction of lower limb defects, including superficial circumflex iliac
               perforator (SCIP), gluteal artery perforator (GAP), thoracodorsal artery perforator (TDAP), deep inferior
               epigastric perforator (DIEP), posterior interosseous artery perforator (PIAP), upper medial thigh perforator,
               and medial sural artery perforator (MSAP) flaps in their 563 cases experience. They propose an algorithm
                                                                 [5]
               for flap selection based on the characteristics of each flap . Other than the already described ALT, SCIP
               and DIEP flaps, GAP flaps appeared to be indicated in moderate size defects located in the posterior body
               surface but, as a drawback, they have a short pedicle and may require supermicrosurgical technique [77,78] .
               TDAP flap on the other hand have a long pedicle and can be utilized as a composite flap by harvesting it
               with scapular bone [79,80] . PIAP and MSAP flaps provide excellent single-stage coverage for small defects in
               the lower leg and foot . This study suggests the reliability of free perforator flap reconstruction for lower
                                  [81]
               extremity defects. Their series of 552 patients had a high success rate (96.2%), even though they treated a
               large number of diabetic limb salvage cases. Previous works reported achieving similar rates of success in
               using perforator flaps in complicated lower extremity reconstructions [17,56,57,74,75] .


               WEIGHT-BEARING ISSUE IN THE LOWER LIMB
               In lower limb reconstruction weight-bearing areas may be involved, where the epidermal-dermal layer
               is thicker and attached, through fibrous connective tissue, to the plantar aponeurosis. Fat lobules are
                                                                                                        [82]
               located within these fibrous septa. This structure provides shock-absorbing function and prevents shear .
               In order to reconstruct this area like-with-like, the medial plantar flap was introduced. It was initially
               described as a cross-leg flap but it has been used since, both as pedicled, for ipsilateral defects, and as a
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