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Page 12 of 15                                          Crowe et al. Plast Aesthet Res 2019;6:4  I  http://dx.doi.org/10.20517/2347-9264.2018.70

               Table 2. Surgical and prosthetic considerations by amputation level
                                               Surgical considerations       Prosthetic and orthotic considerations
                Transmetatarsal amputation  Exact location of transection variable  Partial foot prosthesis with toe filler
                                   Closure via plantar flap or fishmouth incision  Carbon-fiber inlay or spring to provide additional
                                   Consider Achilles lengthening to reduce the risk of   force during terminal stance
                                   equinovarus deformity
                Midfoot amputation   Level of amputation dependent on joint space transected  Similar prosthetic considerations to
                (e.g., Lisfranc and Chopart)  Useful when midfoot joint instability is present  transmetatarsal amputation
                                   Greater propensity for equinovarus deformity and may   Consider contralateral shoe lift if orthotic causes
                                   require a balancing procedure           limb length discrepancy
                Syme amputation    Provides greater lever arm as compared to transtibial   Limb length discrepancy almost always present
                                   amputation                              Device must accommodate bulbous distal limb
                                   Proximal heel pad used for coverage     Prosthetic foot must offload compressive force
                                   Partial weight bearing may proceed in early postoperative   on residual limb
                                   period
                Transtibial amputation  Location of transection important for both lever arm,   Consider componentry of prosthetic prescription
                                   prosthetic accomodation, and soft tissue coverage  individually
                                   Myodesis is preferable if bone quality adequate  Ankle joint axis should be chosen based on
                                   Traction neurectomies should be performed in such a way   patient’s level of functionality
                                   to prevent neuroma formation
                Knee disarticulation  Generally preferable compared to transfemoral amputation  Choice of liner important to accommodate
                                   Gastrocnemius muscle belly may be used to pad distal end  bulbous residual limb
                                   Femoral epiphysis may be left intact in children to allow for   Position of prosthetic knee lies distal to
                                   growth                                  contralateral knee, necessitating shortening of
                                                                           lower leg prosthesis
                Transfemoral amputation  Soft-tissue envelope generally adequate  Socket narrow in mediolateral dimension
                                   Ideally transection occurs no more than 7 cm proximal to   and incorporate ischium to promote femoral
                                   knee joint                              adduction
                                   Preservation and anchoring of adductor magnus improves   Choice of prosthetic joints highly dependent on
                                   position of femur                       patient’s ambulatory status


               processing systems within prosthetic devices and the advent of myoelectric devices represent promising
               advancements in the field of prosthetic restoration. Limitations regarding sensibility and proprioception
               remain a hurdle for emulation of the native limb.


               DECLARATIONS
               Authors’ contributions
               Literature review: Crowe CS, ImpastatoKA, DonaghyAC, Earl C




               Primary manuscript drafting: Crowe CS, ImpastatoKA, DonaghyAC

               Concept design: Crowe CS, Friedly JL, KeysKA

               Substantial manuscript revision: Earl C, Friedly JL, KeysKA
               Availability of data and materials
               Not applicable.
               Financial support and sponsorship
               None.


               Conflicts of interest
               All authors declared that there are no conflicts of interest.


               Ethical approval and consent to participate
               Not applicable.


               Consent for publication
               Not applicable.
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