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Page 122 Constantinides et al. Neuroimmunol Neuroinflammation 2020;7:120-31 I http://dx.doi.org/10.20517/2347-8659.2019.22
Table 1. Overview of the studies with data on classical CSF biomarkers in cohorts with Parkinsonism
Aβ 42 τ Τ τ P-181 Comparison group
Studies in PSP
Holmberg et al. [10] ↔ Ctrl, MSA, PD
Verbeek et al. [11] ↔ Ctrl, MSA, PD
b
Aerts et al. [12] ↔ a ↓ ↑ c ↔ a a. CBD, PD, ctrl
b. CBD
c. PD
a
Hall et al. [13] ↔ ↑ b ↔ c ↓ d a. MSA, CBD, PD, PDD, ctrl
b. DLB
c. ctrl, CBD, MSA
d. ctrl
Schoonenboom et al. [14] ↔ ↔ ↔ DLB, CBD, ctrl
Magdalinou et al. [15] ↔ ↔ ↔ CBD, MSA, PD, ctrl
Constantinides et al. [16] ↔ ↔ ↔ MSA, PD, CBD, ctrl
Noguchi et al. [17] ↓ a ↔ b ↔ b a. ctrl
b. ctrl, CBD
Wagshal et al. [18] ↓ ↓ ↔ ctrl
Schirinzi et al. [19] ↓ ↓ ↓ ctrl
Süssmuth et al. [20] ↔ ↔ ↔ MSA, PD
Studies in CBD
Aerts et al. [12] ↔ a ↑ a ↑ b a. ctrl, PSP, PD
↔ c b. PD
c. ctrl, PSP
b
Constantinides et al. [16] ↓ a ↑ ↔ c ↔ d a. PD
b. ctrl
c. PSP, MSA, PD
d. PSP, MSA, PD, ctrl
Mitani et al. [21] ↑ ctrl
Urakami et al. [22] ↑ ctrl, PSP
Urakami et al. [23] ↑ ctrl, PSP
Hall et al. [13] ↔ ↑ b ↑ ↔ d ↔ ↑ f a. MSA, PSP, PD, PDD, ctrl
e
a
c
b. DLB
c. PD
d. PSP
e. PSP, PD, ctrl
f. MSA
Schoonenboom et al. [14] ↓ ↔ ↔ ctrl
Magdalinou et al. [15] ↔ ↔ ↔ MSA, PSP, PD, ctrl
a
Noguchi et al. [17] ↔ ↓ b ↔ c ↔ c a. PSP
b. ctrl
c. ctrl, PSP
Studies in MSA
Holmberg et al. [10] ↓ PD, PSP, ctrl
Shi et al. [26] ↓ ↔ b ↔ c ↔ c a. ctrl
a
b. PD
c. ctrl,PD
Verbeek et al. [11] ↔ Ctrl, PD
a
Hall et al. [13] ↔ ↑ b ↑ c ↓ d a. MSA, CBD, PD, PDD, ctrl
b. DLB
c. PD, PDD
d. PD, ctrl
Magdalinou et al. [15] ↔ ↔ ↔ CBD, PSP, PD, ctrl
Constantinides et al. [16] ↔ ↔ ↔ PSP, CBD, PD, ctrl
Süssmuth et al. [20] ↔ a ↑ b ↔ c a. PD, PSP
b. ctrl, PD
c. PSP, PD, ctrl
Mollenhauer et al. [27] ↔ ↔ PSP, PD
Abdo et al. [28] ↑ ctrl
Herbert et al. [29] ↑ Ctrl, PD
Abdo et al. [30] ↑ PD
Herbert et al. [31] ↑ PD
Studies in DLB
a
Schoonenboom et al. [14] ↓ ↑ b ↓ ↑ a ↓ ↑ a a. ctrl
b
b
b. AD