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Montabone et al. Neuroimmunol Neuroinflammation 2019;6:7 I http://dx.doi.org/10.20517/2347-8659.2019.09 Page 3 of 7
A B
C
D E
Figure 1. Instrumental imaging of right eye at symptoms presentation. A: colorful fundus photography; B: funduscopic scan with retinal
exudates organizing in macular star appearance; C: OCT of right eye showing retinoic edema with peripapillary fluid; D: fluorescein
angiography showing leakage of vessels from inflamed right optic disc; E: indocyanine green angiography
Neurological findings
A brain tomography was immediately performed to exclude an intracranial mass and one week later she
had a magnetic resonance imaging (MRI) of brain and optic nerves, that resulted normal. Visual evoked
potentials (VEP) showed a severe right delay of conduction (P100 latency was 123 ms) [Figure 2].
Since the ophthalmological pattern was highly suggestive for an inflammatory neuroretinitis, a full blood
analysis for autoimmune and infective causes was performed. Erythrocyte sedimentation rate was mildly
elevated (38 mm/h N.V. 0-15), and serologic test for herpetic viruses including cytomegalovirus and Epstein
Barr showed immunization from previous infections. Serology for toxoplasmosis, syphilis, Lyme disease and
