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Orsucci et al. Neuroimmunol Neuroinflammation 2018;5:7  I  http://dx.doi.org/10.20517/2347-8659.2017.67                Page 3 of 5

               A  Inteross dors I (Spont)                 G  Gastroc caput med (Spont)











                                                      0.1 mV                                        0.1 mV
                                                      10 ms                                         10 ms
               B  Inteross dors I (Spont)                 H  Gastroc caput med (Spont)










                                                      0.1 mV                                        0.1 mV
                                                      10 ms                                          10 ms
               C  Tibialis anterior (Spont)
                                                           I  Gastroc caput med (Spont)










                                                      0.1 mV
                                                      10 ms                                          0.1 mV
               D  Tibialis anterior (Spont)                                                          10 ms
                                                           J  Gastroc caput med (IP)









                                                      0.1 mV                                          2 mV
                                                      10 ms                                           20 ms
               E  Tibialis anterior (Spont)               K  Tibialis anterior (IP)










                                                      0.1 mV                                           2 mV
                                                       10 ms                                           20 ms
                                                           L  Tibialis anterior (IP)
               F  Tibialis anterior (Spont)










                                                      0.1 mV                                           2 mV
                                                      10 ms                                            20 ms
              Figure 1. Continuous spontaneous activity in all the examined muscle districts. Electromyography showing abnormal repetitive spontaneous
              activity of the muscle fibers (doublet, triplet, or multiple single-unit discharges with high, irregular intraburst frequency) in all the muscle
              groups (reported in the figure). (A-E) Right side; (F-G) left side. Spont: spontaneous activity
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