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Page 4 of 4 Orsucci et al. Neuroimmunol Neuroinflammation 2018;5:6 I http://dx.doi.org/10.20517/2347-8659.2017.66

[6]
fetal PCA and ischemic stroke is debated , fetal PCA may have some hemodynamic impact (e.g. faster
[7]
perfusion transit times ipsilateral to fetal origin of the PCA) , and a detrimental interaction of the two
factors (hemodynamics and coagulation) cannot be ruled out.
In conclusion, hematologists, geneticists and neurologists should be aware of this condition, which in most
cases may easily be detectable on routine assays, and hypodysfibrinogenemia should be included among the
[8]
monogenic diseases associated with ischemic stroke in younger adults.

DECLARATIONS
Authors’ contributions
Prepared the manuscript: Orsucci D
Revised the manuscript: Mazzoni M
Clinically studied the patient: Salvetti S, Vista M
Performed the hematological examinations: Margelli M
Performed the angiographic studies: Puglioli M

Financial support and sponsorship
None.

Conflicts of interest
There are no conflicts of interest.

Patient consent
The manuscript does not contain patient identifiable data.

Ethics approval
Not applicable.

Copyright
© The Author(s) 2018.

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