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Dai et al. Neuroimmunol Neuroinflammation 2018;5:28 Neuroimmunology and
DOI: 10.20517/2347-8659.2018.09 Neuroinflammation

Case Report Open Access

Streptococcus gallolyticus meningocephalitis in
adults: the first case report in China

Yue-Man Dai , Min Zhao , Hong-Ji Lu , Li-Xin Wang 2
2
1
2
1 Department of Neurology, The 2nd Teaching Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510120, Guangdong,
China.
2 Department of Neurology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510405, Guangdong, China.

Correspondence to: Dr. Li-Xin Wang, Department of Neurology, Guangdong Provincial Hospital of Chinese Medicine, 111 Dade Road,
Guangzhou 510405, Guangdong, China. E-mail: plawlx@126.com

How to cite this article: Dai YM, Zhao M, Lu HJ, Wang LX. Streptococcus gallolyticus meningocephalitis in adults: the first case
report in China. Neuroimmunol Neuroinflammation 2018;5:28. http://dx.doi.org/10.20517/2347-8659.2018.09

Received: 13 Mar 2018 First Decision: 28 Apr 2018 Revised: 18 May 2018 Accepted: 20 May 2018 Published: 16 Jul 2018

Science Editor: Athanassios P. Kyritsis Copy Editor: Jun-Yao Li Production Editor: Huan-Liang Wu

ABSTRACT
We report on the first case of a Streptococcus gallolyticus meningocephalitis in China. The bacterium was first
isolated from the patient’s cerebrospinal fluid and has so far not been associated with human infections of the
central nervous system. We hope our case report can give some references for the diagnosis and treatment of the
Streptococcus gallolyticus meningocephalitis in China.

Keywords: Streptococcus gallolyticus, meningocephalitis, China, case report, adult

INTRODUCTION
Streptococcus gallolyticus is an uncommon cause of meningocephalitis so far apart from the bacteremia or
the peritonitis. We report one case with meningocephalitis in which Streptococcus gallolyticus was isolated
from the cerebrospinal fluid (CSF). The organisms were seen on a gram-stained preparation of CSF. The
patient had a history of adenocarcinoma of colon and presented with hyperpyrexia, deliration and neck
rigidity. After the antibiotic treatment for 2 weeks, finally he got fully recovery. A review of the literature
revealed only about 42 cases of meningitis due to Streptococcus gallolyticus were reported and the present
case report was the first one from china. The case indicates the importance of laboratory identification of
specific organisms and provides experience in meningocephalitis caused by Streptococcus gallolyticus.

© The Author(s) 2018. Open Access This article is licensed under a Creative Commons Attribution 4.0
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