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Page 6 of 14 Cui et al. Microbiome Res Rep. 2025;4:31 https://dx.doi.org/10.20517/mrr.2025.25
Figure 1. Signaling pathway diagram of SCFAs-mediated inhibition of adipogenesis. SCFAs: Short-chain fatty acids.
Figure 2. Mechanisms of gut microbiota regulation of fat deposition in chickens and pigs. This primarily includes four aspects: SCFAs
inhibit lipogenesis; secondary bile acids bind TGR5 to promote thermogenesis; LPS triggers TLR4-NF-κB-driven inflammation; and
BCAAs activate mTORC1 to stimulate adipogenesis. SCFAs: Short-chain fatty acids; LPS: lipopolysaccharide; NF-κB: nuclear factor-
kappa B; BCAAs: branched-chain amino acids; mTORC1: mechanistic target of rapamycin complex 1.
