Page 111 - Read Online
P. 111
Page 18 of 22 Borrego-Ruiz et al. Microbiome Res Rep. 2025;4:20 https://dx.doi.org/10.20517/mrr.2024.78
gender, shape the developing gut microbiota. PLoS One. 2016;11:e0158498. DOI PubMed PMC
64. Koenig JE, Spor A, Scalfone N, et al. Succession of microbial consortia in the developing infant gut microbiome. Proc Natl Acad Sci
U S A. 2011;108 Suppl 1:4578-85. DOI PubMed PMC
65. Vaishampayan PA, Kuehl JV, Froula JL, Morgan JL, Ochman H, Francino MP. Comparative metagenomics and population dynamics
of the gut microbiota in mother and infant. Genome Biol Evol. 2010;2:53-66. DOI PubMed PMC
66. Yatsunenko T, Rey FE, Manary MJ, et al. Human gut microbiome viewed across age and geography. Nature. 2012;486:222-7. DOI
PubMed PMC
67. Matsuki T, Yahagi K, Mori H, et al. A key genetic factor for fucosyllactose utilization affects infant gut microbiota development. Nat
Commun. 2016;7:11939. DOI PubMed PMC
68. Bergström A, Skov TH, Bahl MI, et al. Establishment of intestinal microbiota during early life: a longitudinal, explorative study of a
large cohort of Danish infants. Appl Environ Microbiol. 2014;80:2889-900. DOI PubMed PMC
69. Pantazi AC, Balasa AL, Mihai CM, et al. Development of gut microbiota in the first 1000 days after birth and potential interventions.
Nutrients. 2023;15:3647. DOI PubMed PMC
70. Borrego-Ruiz A, Borrego JJ. Human gut microbiome, diet, and mental disorders. Int Microbiol. 2025;28:1-15. DOI PubMed PMC
71. George S, Aguilera X, Gallardo P, et al. Bacterial gut microbiota and infections during early childhood. Front Microbiol.
2021;12:793050. DOI PubMed PMC
72. Yassour M, Vatanen T, Siljander H, et al; DIABIMMUNE Study Group. Natural history of the infant gut microbiome and impact of
antibiotic treatment on bacterial strain diversity and stability. Sci Transl Med. 2016;8:343ra81. DOI PubMed PMC
73. Zhong H, Penders J, Shi Z, et al. Impact of early events and lifestyle on the gut microbiota and metabolic phenotypes in young
school-age children. Microbiome. 2019;7:2. DOI PubMed PMC
74. Olszak T, An D, Zeissig S, et al. Microbial exposure during early life has persistent effects on natural killer T cell function. Science.
2012;336:489-93. DOI PubMed PMC
75. Gensollen T, Iyer SS, Kasper DL, Blumberg RS. How colonization by microbiota in early life shapes the immune system. Science.
2016;352:539-44. DOI PubMed PMC
76. Johnson CC, Ownby DR. The infant gut bacterial microbiota and risk of pediatric asthma and allergic diseases. Transl Res.
2017;179:60-70. DOI PubMed PMC
77. Johnson CC, Ownby DR. Allergies and asthma: do atopic disorders result from inadequate immune homeostasis arising from infant
gut dysbiosis? Expert Rev Clin Immunol. 2016;12:379-88. DOI PubMed PMC
78. Björkstén B, Sepp E, Julge K, Voor T, Mikelsaar M. Allergy development and the intestinal microflora during the first year of life. J
Allergy Clin Immunol. 2001;108:516-20. DOI
79. diseases. Curr Opin Allergy Clin Immunol. 2016;16:390-5. DOI PubMed
Kalliomäki M, Kirjavainen P, Eerola E, Kero P, Salminen S, Isolauri E. Distinct patterns of neonatal gut microflora in infants in
whom atopy was and was not developing. J Allergy Clin Immunol. 2001;107:129-34. DOI
80. Fujimura KE, Sitarik AR, Havstad S, et al. Neonatal gut microbiota associates with childhood multisensitized atopy and T cell
differentiation. Nat Med. 2016;22:1187-91. DOI PubMed PMC
81. Penders J, Stobberingh EE, Thijs C, et al. Molecular fingerprinting of the intestinal microbiota of infants in whom atopic eczema was
or was not developing. Clin Exp Allergy. 2006;36:1602-8. DOI
82. Abrahamsson TR, Jakobsson HE, Andersson AF, Björkstén B, Engstrand L, Jenmalm MC. Low diversity of the gut microbiota in
infants with atopic eczema. J Allergy Clin Immunol. 2012;129:434-40, 440.e1. DOI PubMed
83. Cheung MK, Leung TF, Tam WH, et al. Development of the early-life gut microbiome and associations with eczema in a prospective
Chinese cohort. mSystems. 2023;8:e0052123. DOI PubMed PMC
84. Wang M, Karlsson C, Olsson C, et al. Reduced diversity in the early fecal microbiota of infants with atopic eczema. J Allergy Clin
Immunol. 2008;121:129-34. DOI
85. Nylund L, Nermes M, Isolauri E, Salminen S, de Vos WM, Satokari R. Severity of atopic disease inversely correlates with intestinal
microbiota diversity and butyrate-producing bacteria. Allergy. 2015;70:241-4. DOI PubMed
86. Simonyte Sjödin K, Vidman L, Rydén P, West CE. Emerging evidence of the role of gut microbiota in the development of allergic
87. Miteva D, Lazova S, Velikova T. Genetic and epigenetic factors in risk and susceptibility for childhood asthma. Allergies.
2023;3:115-33. DOI
88. Yang IV, Lozupone CA, Schwartz DA. The environment, epigenome, and asthma. J Allergy Clin Immunol. 2017;140:14-23. DOI
PubMed PMC
89. Alsharairi NA. The infant gut microbiota and risk of asthma: the effect of maternal nutrition during pregnancy and lactation.
Microorganisms. 2020;8:1119. DOI PubMed PMC
90. Azad MB, Kozyrskyj AL. Perinatal programming of asthma: the role of gut microbiota. Clin Dev Immunol. 2012;2012:932072. DOI
PubMed PMC
91. Suárez-Martínez C, Santaella-Pascual M, Yagüe-Guirao G, García-Marcos L, Ros G, Martínez-Graciá C. The early appearance of
asthma and its relationship with gut microbiota: a narrative review. Microorganisms. 2024;12:1471. DOI PubMed PMC
92. Arrieta MC, Stiemsma LT, Dimitriu PA, et al; CHILD Study Investigators. Early infancy microbial and metabolic alterations affect
risk of childhood asthma. Sci Transl Med. 2015;7:307ra152. DOI
93. Abrahamsson TR, Jakobsson HE, Andersson AF, Björkstén B, Engstrand L, Jenmalm MC. Low gut microbiota diversity in early

