Page 64 - Read Online

Jiang et al. Microbiome Res Rep 2024;3:47 https://dx.doi.org/10.20517/mrr.2024.12 Page 17 of 20

11. van Passel MW, Kant R, Zoetendal EG, et al. The genome of Akkermansia muciniphila, a dedicated intestinal mucin degrader, and its
use in exploring intestinal metagenomes. PLoS One 2011;6:e16876. DOI PubMed PMC
12. Derrien M, Van Baarlen P, Hooiveld G, Norin E, Müller M, de Vos WM. Modulation of mucosal immune response, tolerance, and
proliferation in mice colonized by the mucin-degrader Akkermansia muciniphila. Front Microbiol 2011;2:166. DOI PubMed PMC
13. Wang L, Christophersen CT, Sorich MJ, Gerber JP, Angley MT, Conlon MA. Low relative abundances of the mucolytic bacterium
Akkermansia muciniphila and Bifidobacterium spp. in feces of children with autism. Appl Environ Microbiol 2011;77:6718-21. DOI
PubMed PMC
14. Kang CS, Ban M, Choi EJ, et al. Extracellular vesicles derived from gut microbiota, especially Akkermansia muciniphila, protect the
progression of dextran sulfate sodium-induced colitis. PLoS One 2013;8:e76520. DOI PubMed PMC
15. Lukovac S, Belzer C, Pellis L, et al. Differential modulation by Akkermansia muciniphila and Faecalibacterium prausnitzii of host
peripheral lipid metabolism and histone acetylation in mouse gut organoids. mBio 2014;5:e01438-14. DOI PubMed PMC
16. Dingemanse C, Belzer C, van Hijum SAFT, et al. Akkermansia muciniphila and Helicobacter typhlonius modulate intestinal tumor
development in mice. Carcinogenesis 2015;36:1388-96. DOI PubMed
17. Ottman N, Huuskonen L, Reunanen J, et al. Characterization of outer membrane proteome of Akkermansia muciniphila reveals sets of
novel proteins exposed to the human intestine. Front Microbiol 2016;7:1157. DOI PubMed PMC
18. Gobert AP, Sagrestani G, Delmas E, et al. The human intestinal microbiota of constipated-predominant irritable bowel syndrome
patients exhibits anti-inflammatory properties. Sci Rep 2016;6:39399. DOI PubMed PMC
19. Guo X, Li S, Zhang J, et al. Genome sequencing of 39 Akkermansia muciniphila isolates reveals its population structure, genomic and
functional diverisity, and global distribution in mammalian gut microbiotas. BMC Genomics 2017;18:800. DOI PubMed PMC
20. Plovier H, Everard A, Druart C, et al. A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium
improves metabolism in obese and diabetic mice. Nat Med 2017;23:107-13. DOI PubMed
21. Wang L, Tang L, Feng Y, et al. A purified membrane protein from Akkermansia muciniphila or the pasteurised bacterium blunts
+
colitis associated tumourigenesis by modulation of CD8 T cells in mice. Gut 2020;69:1988-97. DOI PubMed PMC
22. Bajer L, Kverka M, Kostovcik M, et al. Distinct gut microbiota profiles in patients with primary sclerosing cholangitis and ulcerative
colitis. World J Gastroenterol 2017;23:4548-58. DOI PubMed PMC
23. Kump P, Wurm P, Gröchenig HP, et al. The taxonomic composition of the donor intestinal microbiota is a major factor influencing
the efficacy of faecal microbiota transplantation in therapy refractory ulcerative colitis. Aliment Pharmacol Ther 2018;47:67-77. DOI
PubMed PMC
24. Earley H, Lennon G, Balfe Á, Coffey JC, Winter DC, O’Connell PR. The abundance of Akkermansia muciniphila and its relationship
with sulphated colonic mucins in health and ulcerative colitis. Sci Rep 2019;9:15683. DOI PubMed PMC
25. Van den Bossche L, Hindryckx P, Devisscher L, et al. Ursodeoxycholic acid and its taurine- or glycine-conjugated species reduce
colitogenic dysbiosis and equally suppress experimental colitis in mice. Appl Environ Microbiol 2017;83:e02766-16. DOI PubMed
PMC
26. Lee Y, Sugihara K, Gillilland MG 3rd, Jon S, Kamada N, Moon JJ. Hyaluronic acid-bilirubin nanomedicine for targeted modulation
of dysregulated intestinal barrier, microbiome and immune responses in colitis. Nat Mater 2020;19:118-26. DOI PubMed PMC
27. Alvarado DM, Chen B, Iticovici M, et al. Epithelial indoleamine 2,3-dioxygenase 1 modulates aryl hydrocarbon receptor and notch
signaling to increase differentiation of secretory cells and alter mucus-associated microbiota. Gastroenterology 2019;157:1093-108.
e11. DOI PubMed PMC
28. Yang L, Liu C, Zhao W, et al. Impaired autophagy in intestinal epithelial cells alters gut microbiota and host immune responses. Appl
Environ Microbiol 2018;84:e00880-18. DOI PubMed PMC
29. Zhai R, Xue X, Zhang L, Yang X, Zhao L, Zhang C. Strain-specific anti-inflammatory properties of two Akkermansia muciniphila
strains on chronic colitis in mice. Front Cell Infect Microbiol 2019;9:239. DOI PubMed PMC
30. Bian X, Wu W, Yang L, et al. Administration of Akkermansia muciniphila ameliorates dextran sulfate sodium-induced ulcerative
colitis in mice. Front Microbiol 2019;10:2259. DOI PubMed PMC
31. Johnson CM, Wei C, Ensor JE, et al. Meta-analyses of colorectal cancer risk factors. Cancer Causes Control 2013;24:1207-22. DOI
PubMed PMC
32. Marchesi JR, Adams DH, Fava F, et al. The gut microbiota and host health: a new clinical frontier. Gut 2016;65:330-9. DOI
PubMed PMC
33. Grivennikov SI. Inflammation and colorectal cancer: colitis-associated neoplasia. Semin Immunopathol 2013;35:229-44. DOI
PubMed PMC
34. Zhou X, Chen C, Zhong YN, et al. Effect and mechanism of vitamin D on the development of colorectal cancer based on intestinal
flora disorder. J Gastroenterol Hepatol 2020;35:1023-31. DOI PubMed
35. Fan L, Xu C, Ge Q, et al. A. Muciniphila suppresses colorectal tumorigenesis by inducing TLR2/NLRP3-mediated M1-like TAMs.
Cancer Immunol Res 2021;9:1111-24. DOI PubMed
36. Niederreiter L, Adolph TE, Tilg H. Food, microbiome and colorectal cancer. Dig Liver Dis 2018;50:647-52. DOI PubMed
37. Routy B, Le Chatelier E, Derosa L, et al. Gut microbiome influences efficacy of PD-1-based immunotherapy against epithelial
tumors. Science 2018;359:91-7. DOI PubMed
38. Hou X, Zhang P, Du H, et al. Akkermansia Muciniphila potentiates the antitumor efficacy of FOLFOX in colon cancer. Front
Pharmacol 2021;12:725583. DOI PubMed PMC