Page 75 - Read Online

Boyajian et al. Microbiome Res Rep 2024;3:29 https://dx.doi.org/10.20517/mrr.2024.05 Page 27 of 35

2. Boutari C, Mantzoros CS. A 2022 update on the epidemiology of obesity and a call to action: as its twin COVID-19 pandemic
appears to be receding, the obesity and dysmetabolism pandemic continues to rage on. Metabolism 2022;133:155217. DOI PubMed
PMC
3. Golden A. Obesit’s impact. Nurs Clin North Am 2021;56:xiii-iv. DOI PubMed
4. Afshin A, Forouzanfar MH, Reitsma MB, et al; GBD 2015 Obesity Collaborators. Health effects of overweight and obesity in 195
countries over 25 years. N Engl J Med 2017;377:13-27. DOI PubMed PMC
5. Schnabel F, Kornak U, Wollnik B. Premature aging disorders: a clinical and genetic compendium. Clin Genet 2021;99:3-28. DOI
PubMed
6. United Nations, Department of Economic and Social Affairs Population Division. World Population Prospects 2022: Summary of
Results. Available from: https://www.un.org/development/desa/pd/sites/www.un.org.development.desa.pd/files/wpp2022_summary_
of_results.pdf. [Last accessed on 15 May 2024].
7. Li X, Cao X, Zhang J, et al. Accelerated aging mediates the associations of unhealthy lifestyles with cardiovascular disease, cancer,
and mortality. J Am Geriatr Soc 2024;72:181-93. DOI PubMed PMC
8. Rudnicka E, Napierała P, Podfigurna A, Męczekalski B, Smolarczyk R, Grymowicz M. The World Health Organization (WHO)
approach to healthy ageing. Maturitas 2020;139:6-11. DOI PubMed PMC
9. Kennedy BK, Berger SL, Brunet A, et al. Geroscience: linking aging to chronic disease. Cell 2014;159:709-13. DOI PubMed PMC
10. Li Z, Zhang Z, Ren Y, et al. Aging and age-related diseases: from mechanisms to therapeutic strategies. Biogerontology 2021;22:165-
87. DOI PubMed PMC
11. Xue QL. The frailty syndrome: definition and natural history. Clin Geriatr Med 2011;27:1-15. DOI PubMed PMC
12. López-Otín C, Blasco MA, Partridge L, Serrano M, Kroemer G. The hallmarks of aging. Cell 2013;153:1194-217. DOI PubMed
PMC
13. López-Otín C, Blasco MA, Partridge L, Serrano M, Kroemer G. Hallmarks of aging: an expanding universe. Cell 2023;186:243-78.
DOI PubMed
14. Global BMI Mortality Collaboration; Di Angelantonio E, Bhupathiraju ShN, Wormser D, et al. Body-mass index and all-cause
mortality: individual-participant-data meta-analysis of 239 prospective studies in four continents. Lancet 2016;388:776-86. DOI
PubMed PMC
15. Lung T, Jan S, Tan EJ, Killedar A, Hayes A. Impact of overweight, obesity and severe obesity on life expectancy of Australian
adults. Int J Obes 2019;43:782-9. DOI PubMed
16. Fontaine KR, Redden DT, Wang C, Westfall AO, Allison DB. Years of life lost due to obesity. JAMA 2003;289:187-93. DOI
PubMed
17. Ruze R, Liu T, Zou X, et al. Obesity and type 2 diabetes mellitus: connections in epidemiology, pathogenesis, and treatments. Front
Endocrinol 2023;14:1161521. DOI PubMed PMC
18. Kolb R, Sutterwala FS, Zhang W. Obesity and cancer: inflammation bridges the two. Curr Opin Pharmacol 2016;29:77-89. DOI
PubMed PMC
19. Dikaiou P, Björck L, Adiels M, et al. Obesity, overweight and risk for cardiovascular disease and mortality in young women. Eur J
Prev Cardiol 2021;28:1351-9. DOI
20. Lee TH, Yau SY. From obesity to hippocampal neurodegeneration: pathogenesis and non-pharmacological interventions. Int J Mol
Sci 2020;22:201. DOI PubMed PMC
21. Caballero B. Humans against obesity: who will win? Adv Nutr 2019;10:S4-9. DOI PubMed PMC
22. Tam BT, Morais JA, Santosa S. Obesity and ageing: two sides of the same coin. Obes Rev 2020;21:e12991. DOI PubMed
23. Reyes-Farias M, Fos-Domenech J, Serra D, Herrero L, Sánchez-Infantes D. White adipose tissue dysfunction in obesity and aging.
Biochem Pharmacol 2021;192:114723. DOI PubMed
24. Shinde AB, Song A, Wang QA. Brown adipose tissue heterogeneity, energy metabolism, and beyond. Front Endocrinol
2021;12:651763. DOI PubMed PMC
25. Li QOY, Soro-Arnaiz I, Aragonés J. Age-dependent obesity and mitochondrial dysfunction. Adipocyte 2017;6:161-6. DOI PubMed
PMC
26. Zhang YX, Ou MY, Yang ZH, Sun Y, Li QF, Zhou SB. Adipose tissue aging is regulated by an altered immune system. Front
Immunol 2023;14:1125395. DOI PubMed PMC
27. Man K, Kallies A, Vasanthakumar A. Resident and migratory adipose immune cells control systemic metabolism and thermogenesis.
Cell Mol Immunol 2022;19:421-31. DOI PubMed PMC
28. Kawai T, Autieri MV, Scalia R. Adipose tissue inflammation and metabolic dysfunction in obesity. Am J Physiol Cell Physiol
2021;320:C375-91. DOI PubMed PMC
29. Xu C, Mathews AE, Rodrigues C, et al. Aged garlic extract supplementation modifies inflammation and immunity of adults with
obesity: a randomized, double-blind, placebo-controlled clinical trial. Clin Nutr ESPEN 2018;24:148-55. DOI
30. Hotamisligil GS. Inflammation, metaflammation and immunometabolic disorders. Nature 2017;542:177-85. DOI PubMed
31. Yu L, Chen Y, Tooze SA. Autophagy pathway: cellular and molecular mechanisms. Autophagy 2018;14:207-15. DOI PubMed
PMC
32. Aman Y, Schmauck-Medina T, Hansen M, et al. Autophagy in healthy aging and disease. Nat Aging 2021;1:634-50. DOI PubMed
PMC