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Puhlmann et al. Microbiome Res Rep 2024;3:28  https://dx.doi.org/10.20517/mrr.2024.04  Page 17 of 20

               Authors’ contributions
               Made substantial contributions to the conception and design of the study and performed data analysis and
               interpretation: Puhlmann ML, van de Rakt E, Kerezoudi EN, Rangel I, Brummer RJ, Smidt H, Kaper FS, de
               Vos WM
               Performed data acquisition, as well as providing administrative, technical, and material support: Puhlmann
               ML, van de Rakt E, Kerezoudi EN, Rangel I, Brummer RJ, Smidt H
               Wrote original draft, reviewed, and edited: Puhlmann ML, de Vos WM

               Availability of data and materials
               Data are available in the Supplementary Materials, and 16S rRNA gene amplicon sequences are submitted to
               the European Nucleotide Archive (ENA) under accession numbers PRJEB74436 and PRJEB74437.


               Financial support and sponsorship
               This work was partly supported by the unlimited 2008 Spinoza grant of the Netherlands Organization of
               Scientific Research (NWO) to de Vos WM and a VLAG fellowship grant 2.0 2022/23 to Puhlmann ML.


               Conflicts of interest
               Kaper FS is the founder and CEO of WholeFiber BV and de Vos WM is scientific advisor to WholeFiber
               BV. Other authors declared that there are no conflicts of interest.


               Ethical approval and consent to participate
               The Research Ethics Committee of Örebro University (dnr 2021-05142) approved the study using human
               colonic biopsies. The study was executed conformly with the Declaration of Helsinki and written informed
               consent was obtained from all subjects prior to the study.

               Consent for publication
               Not applicable.

               Copyright
               © The Author(s) 2024.


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