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Page 12 of 15 Spus et al. Microbiome Res Rep 2023;2:33 https://dx.doi.org/10.20517/mrr.2023.20
Figure 5. Shannon diversity index at different time points of propagation. Shannon index was calculated based on the relative
abundance of genetic lineages. Open triangles represent blend A-1 (first biological replicate without phage addition); open squares
represent blend A-2 (second biological replicate without phage addition); closed triangles represent blend B-1 (first biological replicate
with phage addition); closed squares represent blend B-2 (second biological replicate with phage addition).
Figure 6. Log transformed DNA copy numbers of genetic lineages of blends A-1, A-2, B-1 and B-2 in the multi-strain blend throughout
the propagation experiment. Replicates A-1 and A-2 were used as control - no phage cocktail was added. Replicates B-1 and B-2 were
challenged at the onset of the experiment with the cocktail of three phages.
