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D’Aimmo et al. Microbiome Res Rep 2024;3:11  https://dx.doi.org/10.20517/mrr.2023.59  Page 13 of 22









































































                Figure 5. Phylogenomic tree of Bifidobacterium genus describing the origin and the ability of the type strains of species to produce folate.

               In another in vitro folate production study, it has been shown that in the absence of pABA, folate
               production was suppressed or reduced for many strains. Moreover, increasing the concentration of pABA
               led to great variability in folate production . Only for strains of B. adolescentis and B. pseudocatenulatum,
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