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Page 4 of 8  Kheirvari et al. Mini-invasive Surg 2021;5:40  https://dx.doi.org/10.20517/2574-1225.2021.66


 Table 1. Prevalence of micronutrient deficiencies in those younger and older than 45 years of age, with or without a prescription for supplements before surgery and at 12 months after LSG

 Younger than 45 years of age            Older than 45 years of age
 Normal levels of   Post operative   Post operative
 Variables micronutrients in   Pre   deficiency   Supplements   Post operative   1  Pre   deficiency   Supplements   Post operative   2
 normal individuals  operative   without   dose - daily   deficiency with  P-value  operative   without   dose - daily   deficiency with  P-value
 deficiency  intake  supplement  deficiency    intake          supplement
 supplement                   supplement
 n  -  612  306  -  306  -  612  306           -               306             -

 Iron  M: 80-180 mcg/dL   183 (29.9%)  128 (41.83%)  Men and post-  85 (27.77%)  0.00026*  159   136 (44.44%)  18 mg  77 (25.16%)  < 0.00001*
 F: 60-160 mcg/dL  menopausal   (25.98%)
 women: 8 mg
 Menstruating
 females: 18 mg

 Biotin  133-329 pmol/L  60 (9.8%)  103 (33.66%)  30 μg  48 (15.68%)  < 0.00001*  66 (10.78%) 116 (37.9%)  30 μg  32 (10.45%)  < 0.00001*
 Zinc  0.66-1.10 mcg/mL  171 (27.94%) 129 (42.15%)  M: 11 mg   58 (18.95%)  < 0.00001*  171 (27.94%) 134 (43.79%)  11 mg  55 (17.94%)  < 0.00001*
 F: 8 mg
 Selenium  70-150 ng/mL  84 (13.72%)  52 (16.99%)  55 μg  45 (14.7%)  0.4413  91 (14.86%)  61 (19.93%)  55 μg  48 (15.68%)  0.1706

 Folic acid  2.7-17.0 ng/mL  48 (7.84%)  39 (12.74%)  400 μg  27 (8.82%)  0.1187  55 (8.98%)  42 (13.72%)  400 μg  25 (8.16%)  0.0278*
 Riboflavin  4-24 µg/dL  74 (12.09%) 41 (13.39%)  2.4 μg  33 (10.78%)  0.3221  79 (12.90%) 46 (15.03%)  2.4 μg  26 (8.49%)  0.0120*
 Vitamin   200-900 pg/mL  72 (11.76%)  42 (13.72%)  2.4 μg  24 (7.84%)  0.018*  96 (15.68%) 60 (19.6%)  2.4 μg  39 (12.74%)  0.0208*
 B12
 Vitamin B1 2.5-7.5 μg/dL  18 (2.94%)  18 (5.88%)  M: 1.2 mg   6 (1.96%)  0.012*  23 (3.75%)  25 (8.16%)  M: 1.2 mg   15 (4.9%)  0.101
 F: 1.1 mg                                     F: 1.1 mg
 Vitamin A  20-60 mcg/dL  147 (24.01%) 189 (61.76%)  M: 900 mcg   97 (31.69%)  < 0.00001*  158 (25.81%) 180 (58.82%)  M: 900 mcg   82 (26.79%)  < 0.00001*
 F: 700 mcg                                    F: 700 mcg
 Vitamin E  5.5-17 µg/mL  14 (2.28%)  100 (32.67%)  15 mg  59 (19.28%)  0.00016*  153 (25%)  97 (31.69%)  15 mg  43 (14.05%)  < 0.00001*
 Vitamin C  0.6-2 mg/dL  128 (20.91%) 97 (31.69%)  45 mg  70 (22.87%)  0.014*  145   94 (30.71%)  45 mg  67 (21.89%)  0.01314*
                 (23.69%)

 Vitamin D  20-40 ng/mL  172 (28.1%)  104 (33.98%)  15 mcg  41 (13.39%)  < 0.00001*  141 (23.03%) 150 (49.01%)  20 mcg  66 (21.56%)  < 0.00001*

 *  1
 P-value significant at 0.05.  P-value for statistical analysis of variables between the two subgroups of patients who received supplements and patients who did not receive supplements in the younger than 45 years
 2
 group.  P-value for statistical analysis of variables between the two subgroups of patients who received supplements and patients who did not receive supplements in the older than 45 years group.


 were not only better than in the group without a prescription for supplements postoperative, but also better than their evaluations preoperatively [Table 1].
 Prevalent nutritional deficiencies in the group with a prescription for supplements were in vitamin A (31.69% for first group; 26.79% for second group; P =
 0.4354), iron (27.77% for first group; 25.16% for second group; P = 0.7489), vitamin C (22.87% for first group; 21.89% for second group; P = 0.7718), and

 vitamin E (19.28% for first group; 14.05% for second group; P = 0.08186); the P-values for these variables in the groups of those younger and older than 45
 years which received supplements mentioned above were not statistically significant. The analysis of the data revealed that the reduction of nutritional
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