Page 114 - Read Online
P. 114

Young et al. Mini-invasive Surg 2018;2:16  I  http://dx.doi.org/10.20517/2574-1225.2017.50                                          Page 9 of 12

                Prematurity
                Study name
                Abenhaim
                Amsalem
                Ducarme
                Johannsson
                Kjaer
                Lapolla
                Patel

                Santulli
                Stephanson
                Overall


                           0.5                          0.75                                                                                      1.5                                                         2
                                       Less likely for BS Pt              More likely for BS Pt  Graph generated by DistillerSR
                                                    1

                                                   Figure 10. Premature delivery

               PIH
               There was variation among the 8 studies used in this analysis [13,14,16,18,19,22-24] . While the majority of the studies
               showed no difference in the two groups, Parker et al.  showed an increase in PIH. Parker et al.  theorized
                                                           [22]
                                                                                               [22]
               this is likely due to the fact that the average bariatric candidate is white and older which pre-disposes them
               to hypertension.

               GD
               Prior systematic reviews have shown either a decrease or no change in the rates of GD among the bariatric
               surgery patient [10-12] . The 9 studies used in this review are no exception [13,14,16,18-23] . While there were 4 papers
               showing a decrease in the rates of GD [13,16,20,22] , the majority did not show a difference. It has been theorized
               that there is a reduction in the rates of GD after bariatric surgery due to absorption or metabolic changes .
                                                                                                       [24]
               However, our data did not show a difference in the rates of GD between the two groups. This is likely due to
               the metabolic changes associated with prolonged obesity and is not related to surgery.


               IUGR
               Five studies were included in our review of IUGR rates in respect to bariatric surgery [14,16,22-24] . Individually,
               they found either no difference or an increased rate of IUGR among the bariatric surgical patient as compared
               to their control. In analyzing the five studies together, we concluded there was an increased rate of IUGR in
               association with bariatric surgery.


               The explanation for this finding remains unknown. It has been theorized that malabsorption and nutritional
               deficiencies during the pregnancy may lead to the growth restriction; however fetal growth restriction has
               many etiologies including aneuploidy, infection, and congenital malformations . Both malabsorption and
                                                                                  [23]
               nutritional deficiencies are more often associated with gastric bypass procedures rather than the banding
               procedure. A sub analysis to compare the two procedures was not able to be performed as two of the
               studies only included the Roux-en-Y bypass [23,24]  while the other three did not specify the surgical procedure
               performed. Further studies would need to be performed to determine the IUGR rates in bypass versus
               banding patients.
   109   110   111   112   113   114   115   116   117   118   119