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De Luca et al. Mini-invasive Surg 2022;6:13 Mini-invasive Surgery
DOI: 10.20517/2574-1225.2021.127

Original Article Open Access

Robotic radical prostatectomy in post HIFU salvage

setting: tertiary center experience and review of the
current literature

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Stefano De Luca , Sabrina De Cillis , Federico Piramide , Paolo Alessio , Filippo Russo , Daniele
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Amparore , Gabriele Volpi , Stefano Granato , Matteo Manfredi , Cristian Fiori , Enrico Checcucci 1,3,§ ,
Francesco Porpiglia 1,§
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Department of Oncology, Division of Urology, University of Turin, San Luigi Gonzaga Hospital, Orbassano, Turin 10043, Italy.
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Department of Radiology, Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Turin 10060, Italy.
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Department of Surgery, Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Turin 10060, Italy.
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These Authors equally contributed to the first authorship.
§
These Authors equally contributed to the senior authorship.
Correspondence to: Dr. Stefano De Luca, Department of Oncology, Division of Urology, University of Turin, San Luigi Gonzaga
Hospital, Orbassano, Turin 10043, Italy. E-mail: delucastefano@yahoo.it
How to cite this article: De Luca S, De Cillis S, Piramide F, Alessio P, Russo F, Amparore D, Volpi G, Granato S, Manfredi M, Fiori
C, Checcucci E, Porpiglia F. Robotic radical prostatectomy in post HIFU salvage setting: tertiary center experience and review of
the current literature. Mini-invasive Surg 2022;6:13. https://dx.doi.org/10.20517/2574-1225.2021.127
Received: 4 Nov 2021 First Decision: 10 Jan 2022 Revised: 25 Jan 2022 Accepted: 7 Feb 2022 Published: 24 Feb 2022
Academic Editor: Giulio Belli Copy Editor: Xi-Jun Chen Production Editor: Xi-Jun Chen
Abstract
Aim: The purpose of the study was to describe our surgical technique of salvage robot-assisted radical
prostatectomy (sRARP) in patients who underwent primary high-intensity focused ultrasound (HIFU) and to report
the perioperative, functional, and oncological outcomes during the first year follow up. The secondary aim of the
study was to review the current literature evidence on this topic.

Methods: We retrospectively extracted, from our prospective RARP database, all the patients who underwent
sRARP for biochemical recurrence after primary HIFU. All the surgical interventions were performed by a single
surgeon following our total anatomical reconstruction (TAR) technique. Demographics, perioperative, functional,
and oncological results were collected up to one year follow-up.

Results: Eleven patients underwent post-HIFU sRARP with TAR technique at our institution. All the surgical
procedures were uneventful. All the complication recorded were classified as Clavien-Dindo Grade I. Continence
rate at 1-, 3-, 6-, and 12-month post intervention was 36.3%, 45.5%, 63.6 %, and 81.1%, respectively. Medium PSA

© The Author(s) 2022. Open Access This article is licensed under a Creative Commons Attribution 4.0
International License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, sharing,
adaptation, distribution and reproduction in any medium or format, for any purpose, even commercially, as
long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and
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