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Donisi et al. Mini-invasive Surg 2021;5:38 https://dx.doi.org/10.20517/2574-1225.2021.55 Page 7 of 15

Table 2. Laparoscopic-assisted pancreaticoduodenectomy

Period of Surgical Included N of LAS pancreatic
enrollment operation approaches procedures LAS vs. open LAS vs. TLS/robotic

[72]
Staudacher et al. , 2003-2004 PD LAS 4 - -
2005
[85]
Dulucq et al. , 2006 1999-2005 PD LAS, TLS 9 - Similar IBL, OT, LOS
[91]
Pugliese et al. , 2008 2002-2006 PD LAS*, TLS 7 - -
[70]
Cho et al. , 2009 2007-2008 PD LAS 15 - -
[92]
Machado et al. , - PD LAS*, TLS 2 - -
2013
[87]
Kim et al. , 2013 2007-2011 PD LAS*, TLS 10 - -
[73]
Lee et al. , 2013 2009-2012 PD LAS 42 - -
[89]
Langan et al. , 2014 2010-2013 PD LAS, open 27 Reduced LOS -
Better QoL
Similar OT, morbidity rate
[67]
Wang et al. , 2014 2009-2013 PD LAS, open 13 Decreased blood loss, LOS -
Similar complication and mortality rate
[90]
Wellner et al. , 2014 1996-2013 PD LAS, open 40 Decreased need for blood transfusions -
Similar complication and mortality rate
[86]
Speicher et al. , 2014 2010-2013 PD LAS, TLS, open 31 Increased IBL, POPF grade C rate Increased IBL, POPF grade C rate
Similar R0 rate Similar R0 rate
[93]
Liang et al. , 2015 2011-2013 PD LAS*, TLS, open 13 - -
[80]
Piedimonte et al. , 2010-2014 PD LAS, RA 14 - Similar OT, IBL, morbidity rate
2015
[54]
Wang et al. , 2015 2010-2013 PD LAS, TLS 6 - Similar OT, IBL, morbidity
[77]
Mendoza et al. , 2014 PD LAS, open 18 Reduced LOS -
2015 Increased OT
Similar IBL, LN yield, R0 rate, morbidity rate,
POPF rate
[71]
Liu et al. , 2015 2011-2012 PD LAS 21 - -
[88]
Lu et al. , 2016 2012-2015 PD LAS*,TLS 9 - -
[81]
Patel et al. , 2017 2006-2016 PD LAS, TLS 17 - Reduced LOS, length of ICU stay, severe
morbidity, reoperation rate
[94]
Kantor et al. , 2018 2014-2015 PD LAS*, TLS, robotic, 304 - -
open
[95]
Nassour et al. , 2018 2014-2015 PD LAS*, TLS, robotic, 54 - -
open
[79]
Deichmann et al. , 2000-2015 PD LAS, open 60 Decreased OT, LOS, need for blood -
2018 transfusions, CR-POPF rate