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Page 4 of 7 Carilli et al. Mini-invasive Surg 2024;8:9 https://dx.doi.org/10.20517/2574-1225.2023.132

Table 1. Clinical and demographic baseline patients characteristics
N = 12
Age (year), median (IQR) 58 (50-69)
Sex, n (%) Male 9 (75.0)
Female 3 (25.0)
BMI, median (IQR) 23.4 (21.7-24.6)
CCI, n (%) 0-1 10 (83.3)
≥ 2 2 (16.7)
Preoperative Hb (g/dL), median (IQR) 14.4 (13.3-16.3)
Preoperative eGFR (mL/min), median (IQR) 86 (74-105)
Renal tumors per patient, n (%) 2 9 (75.0)
3 2 (16.7)
4 1 (8.3)
Tumor size (mm), median (IQR) 34 (27-41)
R.E.N.A.L. score, median (IQR) 6 (5-7)
Hilar tumor, n (%) No 26 (92.8)
Yes 2 (7.2)

IQR: Interquartile range; BMI: body mass index; CCI: Charlson Comorbidity index; Hb: haemoglobin; eGFR: estimated glomerular filtration rate.

Table 2. Peri- and post-operative outcomes
N = 12
Console time (min), median (IQR) 134 (98-182)
Estimated blood loss (mL), median (IQR) 200 (188-312)
Resection technique, n (%) Enucleation 20 (71.4)
Enucleo-resection 7 (25.0)
Resection 1 (3.6)
Suture technique, n (%) Sutureless 4 (14.3)
Single-layer 17 (60.7)
Double-layer 7 (25.0)
Hemostatic agents, n (%) 18 (64.3)
Intraoperative complications, n (%) 0 (0)
Length of hospital stay (days), median (IQR) 5 (4-6)
Hb at discharge (g/dL), median (IQR) 11.3 (10.5-13.3)
eGFR at discharge (mL/min), median (IQR) 79 (60-105)
eGFR at 30th post-operative day (ml/min), median (IQR) 80 (62-104)
Grade ≥ 2 post-operative complications, n (%) 2 (16.7)
Post-operative readmissions, n (%) 1 (8.3)
Histology, n (%) Benign 6 (21.4)
Malignant 22 (78.6)
Positive surgical margins, n (%) 1 (4.5)

IQR: Interquartile range; Hb: haemoglobin; eGFR: estimated glomerular filtration rate.

ipsilateral renal tumours managed by sequential segmental renal artery clamping RAPN showed good renal
function preservation at five-months follow-up (-9.3% compared to baseline), without major
[15]
complications . Other recent case series have confirmed the feasibility of off-clamp RAPN for multiple
ipsilateral renal tumours [16,17] .