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Sammarco et al. Mini-invasive Surg 2019;3:31  I  http://dx.doi.org/10.20517/2574-1225.2019.33                                    Page 3 of 5


                    Overall   survival  1-year OS  90.4%  3-year OS  66.1  100%  5-year survival   ranges from  25% to 40%




                     Disease free  1-year DFS  83.5%  3-year DFS  41.9%  1-year 89.5%  3-year 35.8%  9.5 months   (media)




                    R0, n   (%)  92%  100%  100%

                    Length   of stay  4.7 ± 1.8

                        6          4.5
                    Mortality (90   days), n (%)  0%  0%  0%





                    Major   morb, n (%)  n.a.  n.a.  Pelvic   abscess   (33.3%)

                 Table 1. Current state of the art of series with syncronous treatment of colorectal liver metastases and primary cancer
                    Morbidity   (%)  27%  25%  66.5%



                     Conv (%)  12%  0%  0%


                    Perop BL   (mL)  200  250  316 for CRLM. Operative time ranged from 198.5 min to 401 min. Perioperative Blood loss ranged from 200 mL to 316 mL. Conversion tax ranged from 0% to  12%. Complications and major morbidity included delayed wound healing after an abdominal perineal resection (APR) and a delayed rectal anastomotic  failure after ileostomy reversal in synchronous resection [11] , 1 postoperative bile leak, 2 heart failure [9] . 90 days mortali



                     OT (min)  210  198.5 ± 98  401


                    Major resection,   n (%)  13.55%  0%   0%





                    Syncronous   resection  4  3  3




                    No. of   Patient  59  20  6      from 4.5 days to 6 days. The rate of R0 resections ranged from 92% to 100%.


                        01/2008 - 02/2018  02/2013 - 06/2014               associated with colorectal resection.

                     Period    05/ 2012 - 04/2018                                      they are expected to be reported in the future studies.   progressive reduction of procedure related costs.





                    Author, type   study  Guerra et al. [9]  Guadagni  et al. [10]  Dwyer et al. [11]  Synchronous treatment  DISCUSSION
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