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Lesch et al. Mini-invasive Surg 2023;7:20  https://dx.doi.org/10.20517/2574-1225.2023.24  Page 5 of 8

               Table 2. List of the 15 test series performed with a total of 150 tests with each setup and the likelihood of secure closure (LOSC)
                                                  Defect        SSSB /                              LOSC
                Series Title      Tissue Defect shape size   Suture   LSLB   Standardization  Amount of   S:W-L-  until
                                                         USP
                                                                                              Ratio
                                                                                   stitches (n)
                                                  (cm)          suture                              ST (%)
                ES 1  P-210-0.2sP-sO-  porcine incision  15  2-0  SSSB  no         23.7       4.4   100
                     IN-MM20-SBu
                ES 2  P-210-0.2sP-sO-  porcine incision  15  2-0  LSLB  no         13.8       4.4   100
                     IN-MM20-LBu
                ES 3  B-210-0.2sP-sO-  bovine incision  15  2-0  SSSB  no          23         4.3   100
                     IN-MM20-SBu
                ES 4  B-210-0.2sP-sO-  bovine incision  15  2-0  LSLB  no          13.8       4.4   100
                     IN-MM20-LBu
                ES 5  P-210-0.2sP-sO-  porcine incision  15  1  SSSB   no          22.4       4.4   100
                     IN-MM1-SBu
                ES 6  P-210-0.2sP-sO-  porcine incision  15  1  LSLB   no          13.9       4.4   100
                     IN-MM1-LBu
                ES 7  B-210-0.2sP-sO-  bovine incision  15  1   SSSB   no          22         4.3   100
                     IN-MM1-SBu
                ES 8  B-210-0.2sP-sO-  bovine incision  15  1   LSLB   no          13.9       4.3   100
                     IN-MM1-LBu
                ES 9  P-210-0.1sP-sO-  porcine incision+circular 15 + 5  2-0  SSSB  yes  21   4.1   100
                     INDC5-PDS20-
                     SBs
                ES 10  P-210-0.1sP-cO-  porcine incision+circular 15 + 5  2-0  SSSB  yes  27  4.5   90
                     INDC5-MM20-
                     SBs
                ES 11  P-210-0.1sP-cO-  porcine incision+circular 15 + 5  2-0  SSSB  yes  23.5  4.3  40
                     INDC5-PDS20-
                     SBs
                ES 12  P-210-0.1sP-cO-  porcine incision+circular 15 + 5  2-0  SSSB  yes  24  4.2   30
                     INDC5-PDS20-
                     SBs 1
                ES 13  P-210-0.1sP-cO-  porcine incision+circular 15 + 5  2-0  SSSB  yes  22  4.1   30
                     INDC5-PDS20-
                     SBs 2
                ES 14  P-180-0.1sP-cO-  porcine incision+circular 15 + 5  2-0  SSSB  yes  22  4.1   50
                     INDC5-PDS20-
                     SBs-1
                ES 15  P-180-0.1sP-cO-  porcine incision+circular 15 + 5  2-0  SSSB  yes  22  4.1   40
                     INDC5-PDS20-
                     SBs-2


                                                       [13]
               closure by combining the influencing factors . However, the success of a suture is limited by external
               influences, e.g., defect size, retention force of the tissue, applied strain, and impact area.

               Previous experiments have shown that the addition of a circular defect to the incision reduces the durability
               of unstandardized wound closure with MonoMax to 0%. Standardization of the suture technique can
                                                           ®
                                                                                                   ®
                                                                                ®
                                         [13]
               increase the durability to 100% . Increasing the impact area and using PDS instead of Monomax sutures
               again lowered the durability. Our experiments revealed clear differences in the durability of sutures with
               Monomax or PDS sutures. This is in contrast to the literature, which indicates only minor differences
                               ®
                        ®
               between various sutures [12,21] .
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