Page 30 - Read Online
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Guerra et al. J Transl Genet Genom 2022;6:304-21 https://dx.doi.org/10.20517/jtgg.2022.08 Page 320
49. Venkatachalam K, Montell C. TRP channels. Annu Rev Biochem 2007;76:387-417. DOI PubMed PMC
50. Kichko TI, Neuhuber W, Kobal G, Reeh PW. The roles of TRPV1, TRPA1 and TRPM8 channels in chemical and thermal sensitivity
of the mouse oral mucosa. Eur J Neurosci 2018;47:201-10. DOI PubMed
51. Alvarez-Berdugo D, Rofes L, Farré R, et al. Localization and expression of TRPV1 and TRPA1 in the human oropharynx and larynx.
Neurogastroenterol Motil 2016;28:91-100. DOI PubMed
52. Hossain MZ, Ando H, Unno S, Masuda Y, Kitagawa J. Activation of TRPV1 and TRPM8 channels in the larynx and associated
laryngopharyngeal regions facilitates the swallowing reflex. Int J Mol Sci 2018;19:4113. DOI PubMed PMC
53. Peier AM, Moqrich A, Hergarden AC, et al. A TRP channel that senses cold stimuli and menthol. Cell 2002;108:705-15. DOI
PubMed
54. Alvarez-Berdugo D, Rofes L, Arreola V, Martin A, Molina L, Clavé P. A comparative study on the therapeutic effect of TRPV1,
TRPA1, and TRPM8 agonists on swallowing dysfunction associated with aging and neurological diseases. Neurogastroenterol Motil
2018;30:e13185. DOI PubMed
55. Cheng I, Sasegbon A, Hamdy S. Effects of pharmacological agents for neurogenic oropharyngeal dysphagia: A systematic review and
meta-analysis. Neurogastroenterol Motil 2022;34:e14220. DOI PubMed
56. Snitker S, Fujishima Y, Shen H, et al. Effects of novel capsinoid treatment on fatness and energy metabolism in humans: possible
pharmacogenetic implications. Am J Clin Nutr 2009;89:45-50. DOI PubMed PMC
57. Shamsi S, Tran H, Tan RS, Tan ZJ, Lim LY. Curcumin, piperine, and capsaicin: a comparative study of spice-mediated inhibition of
human cytochrome P450 isozyme activities. Drug Metab Dispos 2017;45:49-55. DOI PubMed
58. Don CG, Smieško M. DOI PubMed PMC
59. Ikeda J, Kojima N, Saeki K, Ishihara M, Takayama M. Perindopril increases the swallowing reflex by inhibiting substance P
degradation and tyrosine hydroxylase activation in a rat model of dysphagia. Eur J Pharmacol 2015;746:126-31. DOI PubMed
60. Shinohara Y, Origasa H. Post-stroke pneumonia prevention by angiotensin-converting enzyme inhibitors: results of a meta-analysis of
five studies in Asians. Adv Ther 2012;29:900-12. DOI PubMed
61. Lee JS, Chui PY, Ma HM, et al. Does low dose angiotensin converting enzyme inhibitor prevent pneumonia in older people with
neurologic dysphagia - a randomized placebo-controlled trial. J Am Med Dir Assoc 2015;16:702-7. DOI PubMed
62. Chen D, Xing H, Jiang Q, Xiang Y, Hu W, Guo H. Role of levetiracetam in the rehabilitation of dysphagia due to stroke. Int J of
Pharmacol 2017;13:603-11. DOI
63. Monroe MD, Manco K, Bennett R, Huckabee M. Citric acid cough reflex test: Establishing normative data. J Speech Lang Hear
2014;17:216-24. DOI
64. Fujiwara K, Kawamoto K, Shimizu Y, et al. A novel reflex cough testing device. BMC Pulm Med 2017;17:19. DOI PubMed PMC
65. Nurmi HM, Lätti AM, Brannan JD, Koskela HO. Comparison of mannitol and citric acid cough provocation tests. Respir Med
2019;158:14-20. DOI PubMed
66. Krieger DW. Therapeutic drug approach to stimulate clinical recovery after Brain injury. Front Neurol Neurosci 2013:76-87. DOI
PubMed
67. Jayasekeran V, Pendleton N, Holland G, et al. Val66Met in brain-derived neurotrophic factor affects stimulus-induced plasticity in the
human pharyngeal motor cortex. Gastroenterology 2011;141:827-836.e1. DOI PubMed
68. Oh HM, Kim TW, Park HY, Kim Y, Park GY, Im S. Role of rs6265 BDNF polymorphisms and post-stroke dysphagia recovery-A
prospective cohort study. Neurogastroenterol Motil 2021;33:e13953. DOI PubMed
69. Vasant DH, Payton A, Mistry S, Thompson DG, Hamdy S. The val66met polymorphism of brain-derived neurotrophic factor is
associated with human esophageal hypersensitivity. Neurogastroenterol Motil 2013;25:162-e85. DOI PubMed
70. Essa H, Vasant D, Raginis-zborowska A, Payton A, Michou E, Hamdy S. PTU-182 Can response to pharyngeal stimulation in
dysphagic stroke be predicted by bdnf genetic polymorphisms? Gut 2015;64:A143.1-A143. DOI
71. Mentz H, Horan M, Payton A, Ollier W, Pendleton N, Hamdy S. Homozygosity in the ApoE 4 polymorphism is associated with
dysphagic symptoms in older adults. Dis Esophagus 2015;28:97-103. DOI PubMed
72. Raginis-Zborowska A, Mekli K, Payton A, Ollier W, Hamdy S, Pendleton N. Genetic determinants of swallowing impairments among
community dwelling older population. Exp Gerontol 2015;69:196-201. DOI PubMed
73. Katzenschlager R, Sampaio C, Costa J, Lees A. Anticholinergics for symptomatic management of Parkinson’s disease. Cochrane
Database Syst Rev 2003;2002:CD003735. DOI PubMed PMC
74. Schuh MJ, Crosby S. Chronic anticholinergic toxicity discovered in a pharmacogenomics, polypharmacy patient. Sr Care Pharm
2021;36:304-10. DOI PubMed
75. Eum S, Hill SK, Alliey-Rodriguez N, et al. Genome-wide association study accounting for anticholinergic burden to examine cognitive
dysfunction in psychotic disorders. Neuropsychopharmacology 2021;46:1802-10. DOI PubMed PMC
76. Kersten H, Wyller TB, Molden E. Association between inherited CYP2D6/2C19 phenotypes and anticholinergic measures in elderly
patients using anticholinergic drugs. Ther Drug Monit 2014;36:125-30. DOI PubMed
77. Gurocak S, Konac E, Ure I, et al. The impact of gene polymorphisms on the success of anticholinergic treatment in children with
overactive bladder. Dis Markers 2015;2015:732686. DOI PubMed PMC
78. Villa A, Connell CL, Abati S. Diagnosis and management of xerostomia and hyposalivation. Ther Clin Risk Manag 2015;11:45-51.
DOI PubMed PMC
79. Endo T, Nakajima M, Fukami T, et al. Genetic polymorphisms of CYP2A6 affect the in vivo pharmacokinetics of pilocarpine.

