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Page 96 Oquendo et al. J Transl Genet Genom 2021;5:89-111 https://dx.doi.org/10.20517/jtgg.2021.04
Figure 3. (A) Mutation frequency (%) of recurrently mutated genes in splenic marginal zone lymphoma (SMZL). The frequency was
calculated using a systematically collated database of published mutations and genes are grouped according to affected pathways.
Detailed list and description of mutations, including datasets used, can be accessed in the supplementary material from previous
published work [53] . (B) Word cloud of gene symbols that have been found mutated in SMZL. The size of each gene symbol is proportional
to the frequency of mutations in SMZL. (C) Lolliplot of NOTCH2, KLF2 and TP53. The figure illustrates a linear protein representing each
gene with its respective domains. The height represents the number of variants reported in the literature and circle colour identifies the
type of mutation. Data obtained from Jaramillo Oquendo et al. [53] , 2019.
