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Financial support and sponsorship
The set-up of the ICC was funded by grants from the National Medical Research Council, Singapore, and
NUHS, awarded to Foo RSY.

Conflicts of interest
All authors declared that there are no conflicts of interest.

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Copyright
© The Author(s) 2023.

REFERENCES
1. Birger M, Kaldjian AS, Roth GA, Moran AE, Dieleman JL, Bellows BK. Spending on cardiovascular disease and cardiovascular risk
factors in the United States: 1996 to 2016. Circulation 2021;144:271-82. DOI PubMed PMC
2. Townsend N, Kazakiewicz D, Lucy Wright F, et al. Epidemiology of cardiovascular disease in Europe. Nat Rev Cardiol
2022;19:133-43. DOI
3. Heather JM, Chain B. The sequence of sequencers: the history of sequencing DNA. Genomics 2016;107:1-8. DOI PubMed PMC
4. Spertus JA, Fine JT, Elliott P, et al. Mavacamten for treatment of symptomatic obstructive hypertrophic cardiomyopathy
(EXPLORER-HCM): health status analysis of a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet 2021;397:2467-
75. DOI PubMed
5. FDA. FDA approves new drug to improve heart function in adults with rare heart condition. Available from: https://www.fda.gov/
drugs/news-events-human-drugs/fda-approves-new-drug-improve-heart-function-adults-rare-heart-condition [Last accessed on 20
Feb 2023].
6. Musunuru K, Hershberger RE, Day SM, et al. Genetic testing for inherited cardiovascular diseases: a scientific statement from the
american heart association. Circ Genom Precis Med 2020;13:e000067. DOI PubMed
7. Landstrom AP, Kim JJ, Gelb BD, et al. Genetic testing for heritable cardiovascular diseases in pediatric patients: a scientific
statement from the american heart association. Circ Genom Precis Med 2021;14:e000086. DOI PubMed PMC
8. Maron BJ, McKenna WJ, Danielson GK, et al. American college of cardiology/european society of cardiology clinical expert
consensus document on hypertrophic cardiomyopathy. A report of the American college of cardiology foundation task force on
clinical expert consensus documents and the European society of cardiology committee for practice guidelines. J Am Coll Cardiol
2003;42:1687-713. DOI
9. Weintraub RG, Semsarian C, Macdonald P. Dilated cardiomyopathy. Lancet 2017;390:400-14. DOI PubMed
10. Hershberger RE, Hedges DJ, Morales A. Dilated cardiomyopathy: the complexity of a diverse genetic architecture. Nat Rev Cardiol
2013;10:531-47. DOI PubMed
11. McKenna WJ, Judge DP. Epidemiology of the inherited cardiomyopathies. Nat Rev Cardiol 2021;18:22-36. DOI PubMed
12. Corrado D, Basso C, Judge DP. Arrhythmogenic cardiomyopathy. Circ Res 2017;121:784-802. DOI
13. Elliott PM, Anastasakis A, Borger MA, et al. 2014 ESC guidelines on diagnosis and management of hypertrophic cardiomyopathy:
the task force for the diagnosis and management of hypertrophic cardiomyopathy of the European society of cardiology (ESC). Eur
Heart J 2014;35:2733-79. DOI PubMed
14. Maron BJ, Doerer JJ, Haas TS, Tierney DM, Mueller FO. Sudden deaths in young competitive athletes: analysis of 1866 deaths in the
United States, 1980-2006. Circulation 2009;119:1085-92. DOI PubMed
15. Podrid PJ, Myerburg RJ. Epidemiology and stratification of risk for sudden cardiac death. Clin Cardiol 2005;28:I3-11. DOI PubMed
16. Wilde AAM, Amin AS, Postema PG. Diagnosis, management and therapeutic strategies for congenital long QT syndrome. Heart
2022;108:332-8. DOI PubMed PMC
17. Maron BJ, Maron MS. Hypertrophic cardiomyopathy. Lancet 2013;381:242-55. DOI
18. Mazzarotto F, Olivotto I, Boschi B, et al. Contemporary insights into the genetics of hypertrophic cardiomyopathy: toward a new era
in clinical testing? J Am Heart Assoc 2020;9:e015473. DOI PubMed PMC