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Hadadi et al. J Cancer Metastasis Treat 2018;4:25 I http://dx.doi.org/10.20517/2394-4722.2018.22 Page 15 of 15

antioxidant intake, and breast cancer risk: results from the Shanghai Breast Cancer Study. Breast Cancer Res 2004;6:R647-55.
24. Roy D, Liehr JG. Estrogen, DNA damage and mutation. Mutat Res 1999;424:107-15.
25. Galati G, O’Brien PJ. Potential toxicity of flavonoids and other dietary phenolics: significance for their chemopreventive and anticancer
properties. Free Radic Biol Med 2004;37:287-303.
26. Bonofiglio D, Giordano C, de Amicis F, Lanzino M, Ando S. Natural products aspromising antitumoral agents in breast cancer: mechanisms
of action and moleculartargets. Mini Rev Med Chem 2016;16:596-604.
27. Krishna KL, Paridhavi M, Patel JA. Review on nutritional, medicinal and pharmacological properties of papaya (Carica papaya Linn.). Nat
Prod Rad 2008;7:364-73.
28. Lohsoonthorn P, Danvivat D. Colorectal cancer risk factors: a case-control study in Bangkok. Asia Pac J Public Health 1995;8:118-22.
29. Shahar S, Shafurah S, Shaari H, Rajikan R, Rajab NF, Golkhalkhali B, Zainuddin ZM. Roles of diet, lifetime physical activity and oxidative
DNA damage in the occurrence of prostate cancer among men in Klang Valley, Malaysia. Asian Pac J Cancer Prev 2011;12:605-11.
30. Pandey S, Walpole C, Cabot PJ, Shaw PN, Batra J, Hewavitharana AK. Selective anti-proliferative activities of Carica papaya leaf juice
extracts against prostate cancer. Biomed Pharmacother 2017;89:515-23.
31. Siegel EM, Salemi JL, Villa LL, Ferenczy A, Franco EL, Giuliano AR. Dietary consumption of antioxidant nutrients and risk of incident
cervical intraepithelial neoplasia. Gynecol Oncol 2010;18:289-94.
32. Zhang CX, Ho SC, Chen YM, Fu JH, Cheng SZ, Lin FY. Greater vegetable and fruit intake is associated with a lower risk of breast cancer
among Chinese women. Int J Cancer 2009;125:181-8.
33. Nakamura Y, Yoshimoto M, Murata Y, Shimoishi Y, Asai Y, Park EY, Sato K, Nakamura Y. Papaya seed represents a rich source of
biologically active isothiocyanate. J Agric Food Chem 2007;55:4407-13.
34. Garcia-Solis P, Yahia EM, Morales-Tlalpan V, Diaz-Munoz M. Screening of antiproliferative effect of aqueous extracts of plant foods
consumed in Mexico on the breast cancer cell line MCF-7. Int J Food Sci Nutr 2009;60:32-46.
35. Otsuki N, Dang NH, Kumagai E, Kondo A, Iwata S, Morimoto C. Aqueous extract of Carica papaya leaves exhibits anti-tumor activity and
immunomodulatory effects. J Ethnopharmacol 2010;127:760-7.
36. Sancho L, Yahia E, García-Solís P, González-Aguilar G. Inhibition of proliferation of breast cancer cells MCF7 and MDA-MB-231 by
lipophilic extracts of papaya (Carica papaya L. var. Maradol) fruit. Food Nutr Sci 2014;5:2097-103.
37. Kaur C, Kapoor HC. Anti-oxidant activity and total phenolic content of some Asian vegetables. Int J Food Sci Technol 2002;37:153-61.
38. Chang C, Yang M, Wen H, Chern J. Estimation of total flavonoid content inpropolis by two complementary colorimetric methods. J Food
Drug Anal 2002;10:178-82.
39. Villano D, Fernandez-Pachon MS, Moya ML. Troncoso AM, Garcıa-Parrilla MC. Radical scavenging ability of polyphenolic compounds
towards DPPH free radical. Talanta 2007;71:230-5.
40. Álvarez R, Araya H, Navarro-Lisboa R, Lopez de Dicastillo C. Evaluation of polyphenol content and antioxidant capacity of fruits and
vegetables using a modified enzymatic extraction. Food Technol Biotechnol 2016;54:462-7.
41. Turkmen N, Sari F, Velioglu YS. Effects of extraction solvents on concentration and antioxidant activity of black and black mate tea
polyphenols determined by ferroustartrate and Foline-Ciocalteu methods. Food Chem 2006;99:835-41.
42. Dai J, Mumper RJ. Plant phenolics: extraction, analysis and their antioxidant andanticancer properties. Molecules 2010;15:7313-52.
43. Tsao R. Chemistry and biochemistry of dietary polyphenols. Nutrients 2010;2:1231-46.
44. Shirode AB, Kovvuru P, Chittur SV, Henning SM, Heber D, Reliene R. Antiproliferative effects of pomegranate extract in MCF-7 breast
cancer cells are associated with reduced DNA repair gene expression and induction of double strand breaks. Mol Carcinog 2004;53:458-70.
45. Nguyen TT, Parat MO, Shaw PN, Hewavitharana AK, Hodson MP. Traditional aboriginal preparation alters the chemical profile of carica
papaya leaves and impacts on cytotoxicity towards human squamous cell carcinoma. PLoS One 2016;1: e0147956.
46. Aravind G, Bhowmik D, Duraivel S, Harish G. Traditional and medicinal uses of carica papaya. J Med Plants Stud 2013;1:7-15.
47. Aruljothi S, Uma C, Sivagurunathan P, Bhuvaneswari M. Investigation on antibacterial activity of carica papaya leaf extracts against wound
infection-causing bacterial. Int J Res Stud Biosci 2004;11:8-12.
48. Trock BJ. Breast cancer in African American women: epidemiology and tumor biology. Breast Cancer Res Treat 1996;40:11-24.
49. Edwardson D, Chewchuk S, Parissenti AM. Resistance to Anthracyclines and Taxanes in Breast Cancer. In: Ahmad A, editor. Breast Cancer
Metastasis and Drug Resistance. New York, NY: Springer; 2013. p. 227-47.