Page 33 - Read Online
P. 33

associated with reciprocal changes in JAGGED1  and manic fringe   Genes Dev 2002;16:2252-63.
               expression linked to notch activation. J Virol 2004;78:8687-700.  178.  Tan MJ,  White EA, Sowa ME, Harper JW, Aster JC, Howley PM.
            166. Kuncharin  Y, Sangphech N, Kueanjinda P,  Bhattarakosol P,  Palaga   Cutaneous beta-human papillomavirus E6 proteins bind Mastermind-
               T. MAML1 regulates cell viability via the NF-kappaB  pathway  in   like coactivators and repress Notch signaling. Proc Natl Acad Sci U S A
               cervical  cancer cell  lines.  Exp Cell  Res 2011;317:1830-40.  2012;109:E1473-80.
            167.  Rangarajan A, Syal R, Selvarajah S, Chakrabarti O, Sarin A, Krishna S.   179. Rozenblatt-Rosen  O,  Deo  RC,  Padi  M, Adelmant  G,  Calderwood
               Activated Notch1 signaling cooperates with papillomavirus oncogenes   MA, Rolland T, Grace M, Dricot A, Askenazi M, Tavares M, Pevzner
               in  transformation  and  generates  resistance  to  apoptosis  on  matrix   SJ, Abderazzaq  F,  Byrdsong D,  Carvunis AR,  Chen AA,  Cheng J,
               withdrawal through PKB/ Akt. Virology 2001;286:23-30.
            168. Nair P, Somasundaram K, Krishna S.  Activated Notch1  inhibits   Correll M, Duarte M, Fan C, Feltkamp MC, Ficarro SB, Franchi R,
               p53-induced  apoptosis and  sustains transformation  by  human   Garg BK,  Gulbahce N, Hao T, Holthaus AM, James R, Korkhin A,
               papillomavirus type 16 E6 and E7 oncogenes through a PI3K-PKB/  Litovchick L, Mar JC, Pak TR, Rabello S, Rubio R,  Shen Y,  Singh
               Akt-dependent pathway. J Virol 2003;77:7106-12.    S,  Spangle  JM, Tasan  M, Wanamaker  S,  Webber  JT,  Roecklein-
            169.  Veeraraghavalu K, Subbaiah VK, Srivastava S, Chakrabarti O,  Syal   Canfield  J,  Johannsen  E,  Barabasi  AL,  Beroukhim  R,  Kieff  E,
               R, Krishna S. Complementation  of human  papillomavirus type 16   Cusick ME, Hill DE, Munger K,  Marto  JA,  Quackenbush  J,  Roth
               E6 and E7 by Jagged1-specific Notch1-phosphatidylinositol 3-kinase   FP,  DeCaprio  JA,  Vidal  M.  Interpreting cancer  genomes using
               signaling  involves pleiotropic  oncogenic functions  independent  of   systematic  host  network  perturbations  by tumour  virus proteins.
               CBF1;Su(H);Lag-1 activation. J Virol 2005;79:7889-98.  Nature 2012;487:491-5.
            170. Ramdass B, Maliekal  TT, Lakshmi  S, Rehman  M, Rema  P,   180. Brimer N, Lyons  C,  Wallberg  AE,  Vande  Pol SB.  Cutaneous
               Nair  P,  Mukherjee G,  Reddy  BK, Krishna  S, Radhakrishna  Pillai   papillomavirus E6 oncoproteins associate with MAML1 to  repress
               M. Coexpression of Notch1  and NF-kappaB  signaling  pathway   transactivation and NOTCH signaling. Oncogene 2012;31:4639-46.
               components in human cervical cancer progression. Gynecol Oncol   181. Meyers JM, Spangle JM, Munger K.  The  human papillomavirus
               2007;104:352-61.                                   type  8 E6 protein  interferes with  NOTCH  activation  during
            171.  Weijzen  S,  Zlobin A,  Braid  M,  Miele  L,  Kast  WM.  HPV16  E6   keratinocyte differentiation. J Virol 2013;87:4762-7.
               and E7  oncoproteins  regulate  Notch-1 expression and cooperate to   182. Song  LL,  Peng Y, Yun  J,  Rizzo  P,  Chaturvedi  V,  Weijzen  S,  Kast
               induce transformation. J Cell Physiol 2003;194:356-62.
            172. Vliet-Gregg  PA,  Hamilton  JR,  Katzenellenbogen  RA.  NFX1-123   WM, Stone PJ,  Santos L, Loredo A, Lendahl U,  Sonenshein  G,
               and human papillomavirus  16E6 increase  Notch  expression  in   Osborne  B, Qin  JZ, Pannuti  A,  Nickoloff BJ,  Miele  L.  Notch-1
               keratinocytes. J Virol 2013;87:13741-50.           associates  with  IKKalpha  and  regulates IKK  activity  in  cervical
            173. Vliet-Gregg  PA,  Hamilton  JR,  Katzenellenbogen  RA.  Human   cancer cells. Oncogene 2008;27:5833-44.
               papillomavirus  16E6  and  NFX1-123  potentiate  Notch  signaling   183.  Henken  FE, De-Castro  Arce J, Rosl  F, Bosch L, Meijer CJ,
               and differentiation without activating  cellular  arrest.  Virology   Snijders PJ, Steenbergen RD. The functional role of Notch  signaling
               2015;478:50-60.                                    in HPV-mediated transformation is dose-dependent and  linked to AP-1
            174. Rangarajan A, Talora C, Okuyama R, Nicolas M, Mammucari C, Oh   alterations. Cell Oncol (Dordr) 2012;35:77-84.
               H, Aster  JC,  Krishna  S,  Metzger  D,  Chambon  P,  Miele  L, Aguet   184. Agrawal  N,  Frederick  MJ,  Pickering  CR,  Bettegowda  C,  Chang
               M,  Radtke  F,  Dotto  GP.  Notch signaling is a direct determinant of   K, Li RJ, Fakhry  C, Xie  TX,  Zhang  J,  Wang  J,  Zhang  N,  El-
               keratinocyte  growth  arrest  and entry into differentiation. EMBO J   Naggar AK,  Jasser SA, Weinstein JN, Trevino  L,  Drummond  JA,
               2001;20:3427-36.                                   Muzny  DM,  Wu  Y,  Wood  LD,  Hruban  RH,  Westra  WH,  Koch
            175. Koh LF, Ng BK,  Bertrand J, Thierry F. Transcriptional  control  of   WM, Califano JA, Gibbs RA, Sidransky D, Vogelstein B, Velculescu
               late  differentiation in human keratinocytes  by  TAp63 and  Notch.   VE, Papadopoulos N, Wheeler DA, Kinzler KW, Myers JN. Exome
               Exp Dermatol 2015;24:754-60.                       sequencing  of  head  and  neck  squamous  cell carcinoma  reveals
            176.  Kagawa S, Natsuizaka M, Whelan KA, Facompre N, Naganuma S,
               Ohashi S, Kinugasa H, Egloff AM, Basu D, Gimotty PA, Klein-Szanto   inactivating mutations in NOTCH1. Science 2011;333:1154-7.
               AJ, Bass AJ, Wong KK, Diehl JA, Rustgi AK, Nakagawa H. Cellular   185. Seiwert TY,  Zuo Z,  Keck MK,  Khattri A,  Pedamallu CS,  Stricker
               senescence checkpoint function determines differential Notch1-  T,  Brown  C,  Pugh  TJ,  Stojanov  P,  Cho  J,  Lawrence  MS,  Getz
               dependent oncogenic and tumor-suppressor activities.  Oncogene   G, Bragelmann  J, DeBoer  R,  Weichselbaum RR,  Langerman
               2015;34:2347-59.                                   A,  Portugal  L,  Blair  E,  Stenson  K,  Lingen  MW,  Cohen  EE,
            177.  Talora C, Sgroi DC, Crum CP, Dotto GP. Specific down-modulation   Vokes EE, White KP, Hammerman PS. Integrative  and comparative
               of Notch1 signaling in cervical cancer cells is required for sustained   genomic analysis of HPV-positive and HPV-negative head and neck
               HPV-E6/E7 expression and late steps  of malignant transformation.   squamous cell carcinomas. Clin  Cancer Res 2015;21:632-41.























                        Journal of Cancer Metastasis and Treatment  ¦  Volume 2 ¦ Issue 1 ¦ January 15, 2016 ¦  23
   28   29   30   31   32   33   34   35   36   37   38