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Figure 1: Intraorbital localization of well-differentiated neuroendocrine tumour (G1) of the ileo-cecal valve. MRI of the brain, head and face MRI: sagittal
(A) and coronal (B) views. Lesion occupying the great part of the right orbit, and dislocating the optic nerve, though maintaining a cleavage plan from its
meningeal structures. MRI: magnetic resonance imaging

Figure 2: Well-differentiated neuroendocrine tumor (G1) of the ileo-cecal valve. (A) Mucosal ulceration (arrow, X10); (B) positivity of neoplastic nests for
Chromogranin A (CgA) in the submucosa (X10); (C) muscolar layer neoplasitic invasion and positivity for CgA (X4); (D) piercing serosa positivity for CgA
(arrow, X10); (E) serotonin stains the enterochromaffin cells (EC) (X20); (F) mindbomb homolog 1/ki-67 proliferation index below 2% (arrow, X40)
The physical examination confirmed a slight right eyeball head and neck confirmed the presence of the previously
ptosis without significant visual function impairment; described lesion, occupying the great part of the right
neither symptoms nor signs of carcinoid syndrome were orbit and dislocating the optic nerve, though maintaining
present, the laboratory routine blood tests as complete a cleavage plan from its meningeal structures [Figure 1].
blood count, kidney and liver function tests and electrolyte
levels resulted in range. The Octreoscan showed pathological uptake of the tracer
in the right intraorbital space and in the right iliac fossa.
The thorax and abdominal CT scan showed a lobulated An endoscopic biopsy of the sub mucosal lesion found on
mass with a maximum diameter of 37 mm at the ileocecal the ileocecal valve during a pan colonoscopy confirmed
valve level. A magnetic resonance imaging of the brain, the primary site of the well differentiated, neuroendocrine
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Journal of Cancer Metastasis and Treatment ¦ Volume 2 ¦ August 31, 2016 ¦