Page 41 - Read Online
P. 41

D'Souza et al. J Cancer Metastasis Treat 2022;8:28  https://dx.doi.org/10.20517/2394-4722.2022.51  Page 13 of 15

               34.       Zhong XS, Matsushita M, Plotkin J, Riviere I, Sadelain M. Chimeric antigen receptors combining 4-1BB and CD28 signaling
                    domains augment PI3kinase/AKT/Bcl-XL activation and CD8+ T cell-mediated tumor eradication. Mol Ther 2010;18:413-20.  DOI
                    PubMed  PMC
               35.       Chang K, Pai LH, Batra JK, Pastan I, Willingham MC. Characterization of the antigen (CAK1) recognized by monoclonal antibody
                    K1 present on ovarian cancers and normal mesothelium. Cancer Res 1992;52:181-6.  PubMed
               36.       Pastan I, Hassan R. Discovery of mesothelin and exploiting it as a target for immunotherapy. Cancer Res 2014;74:2907-12.  DOI
                    PubMed  PMC
               37.       Morello A, Sadelain M, Adusumilli PS. Mesothelin-targeted CARs: driving T cells to solid tumors. Cancer Discov 2016;6:133-46.
                    DOI  PubMed  PMC
               38.       Bera TK, Pastan I. Mesothelin is not required for normal mouse development or reproduction. Mol Cell Biol 2000;20:2902-6.  DOI
               39.       Castelletti L, Yeo D, van Zandwijk N, Rasko JEJ. Anti-mesothelin CAR T cell therapy for malignant mesothelioma. Biomark Res
                    2021;9:11.  DOI
               40.       Klampatsa A, Dimou V, Albelda SM. Mesothelin-targeted CAR-T cell therapy for solid tumors. Expert Opin Biol Ther 2021;21:473-
                    86.  DOI  PubMed
               41.       Klampatsa A, Achkova DY, Davies DM, et al. Intracavitary “T4 immunotherapy” of malignant mesothelioma using pan-ErbB re-
                    targeted CAR T-cells. Cancer Lett 2017;393:52-9.  DOI  PubMed
               42.       Al-Taei S, Salimu J, Lester JF, et al. Overexpression and potential targeting of the oncofoetal antigen 5T4 in malignant pleural
                    mesothelioma. Lung Cancer 2012;77:312-8.  DOI  PubMed
               43.       Klampatsa A, Haas AR, Moon EK, Albelda SM. Chimeric antigen receptor (CAR) T cell therapy for malignant pleural mesothelioma
                    (MPM). Cancers (Basel) 2017;9:115.  DOI  PubMed  PMC
               44.       Thayaparan T, Petrovic RM, Achkova DY, et al. CAR T-cell immunotherapy of MET-expressing malignant mesothelioma.
                    Oncoimmunology 2017;6:e1363137.  DOI  PubMed  PMC
               45.       Hyrenius-Wittsten A, Su Y, Park M, et al. SynNotch CAR circuits enhance solid tumor recognition and promote persistent antitumor
                    activity in mouse models. Sci Transl Med 2021;13:eabd8836.  DOI  PubMed  PMC
               46.       Bughda R, Dimou P, D’Souza RR, Klampatsa A. Fibroblast activation protein (FAP)-targeted CAR-T cells: launching an attack on
                    tumor stroma. Immunotargets Ther 2021;10:313-23.  DOI  PubMed  PMC
               47.       Petrausch U, Schuberth PC, Hagedorn C, et al. Re-directed T cells for the treatment of fibroblast activation protein (FAP)-positive
                    malignant pleural mesothelioma (FAPME-1). BMC Cancer 2012;12:615.  DOI  PubMed  PMC
               48.       Schuberth PC, Hagedorn C, Jensen SM, et al. Treatment of malignant pleural mesothelioma by fibroblast activation protein-specific
                    re-directed T cells. J Transl Med 2013;11:187.  DOI  PubMed  PMC
               49.       Hiltbrunner S, Britschgi C, Schuberth P, et al. Local delivery of CAR T cells targeting fibroblast activation protein is safe in patients
                    with pleural mesothelioma: first report of FAPME, a phase I clinical trial. Ann Oncol 2021;32:120-1.  DOI  PubMed
               50.       Blum Y, Meiller C, Quetel L, et al. Dissecting heterogeneity in malignant pleural mesothelioma through histo-molecular gradients for
                    clinical applications. Nat Commun 2019;10:1333.  DOI  PubMed  PMC
               51.       Yoshikawa Y, Sato A, Tsujimura T, et al. Frequent inactivation of the BAP1 gene in epithelioid-type malignant mesothelioma.
                    Cancer Sci 2012;103:868-74.  DOI  PubMed  PMC
               52.       Kiyotani K, Park JH, Inoue H, et al. Integrated analysis of somatic mutations and immune microenvironment in malignant pleural
                    mesothelioma. Oncoimmunology 2017;6:e1278330.  DOI  PubMed  PMC
               53.       Junttila MR, de Sauvage FJ. Influence of tumour micro-environment heterogeneity on therapeutic response. Nature 2013;501:346-54.
                    DOI  PubMed
               54.       Oehl K, Vrugt B, Opitz I, Meerang M. Heterogeneity in malignant pleural mesothelioma. Int J Mol Sci 2018;19:1603.  DOI  PubMed
                    PMC
               55.       Lee HS, Jang HJ, Choi JM, et al. Comprehensive immunoproteogenomic analyses of malignant pleural mesothelioma. JCI Insight
                    2018;3:98575.  DOI  PubMed  PMC
               56.       Chen R, Lee WC, Fujimoto J, et al. Evolution of genomic and T-cell repertoire heterogeneity of malignant pleural mesothelioma
                    under dasatinib treatment. Clin Cancer Res 2020;26:5477-86.  DOI  PubMed  PMC
               57.       Sneddon S, Rive CM, Ma S, et al. Identification of a CD8+ T-cell response to a predicted neoantigen in malignant mesothelioma.
                    Oncoimmunology 2020;9:1684713.  DOI  PubMed  PMC
               58.       Mansfield AS, Peikert T, Smadbeck JB, et al. Neoantigenic potential of complex chromosomal rearrangements in mesothelioma. J
                    Thorac Oncol 2019;14:276-87.  DOI  PubMed  PMC
               59.       Majzner RG, Mackall CL. Tumor antigen escape from CAR T-cell therapy. Cancer Discov 2018;8:1219-26.  DOI  PubMed
               60.       Rafiq S, Hackett CS, Brentjens RJ. Engineering strategies to overcome the current roadblocks in CAR T cell therapy. Nat Rev Clin
                    Oncol 2020;17:147-67.  DOI  PubMed  PMC
               61.       Minnema-Luiting J, Vroman H, Aerts J, Cornelissen R. Heterogeneity in immune cell content in malignant pleural mesothelioma. Int
                    J Mol Sci 2018;19:1041.  DOI  PubMed  PMC
               62.       Newick K, O’Brien S, Moon E, Albelda SM. CAR T cell therapy for solid tumors. Annu Rev Med 2017;68:139-52.  DOI  PubMed
               63.       Wei J, Han X, Bo J, Han W. Target selection for CAR-T therapy. J Hematol Oncol 2019;12:62.  DOI  PubMed  PMC
               64.       Valitutti S, Müller S, Cella M, Padovan E, Lanzavecchia A. Serial triggering of many T-cell receptors by a few peptide-MHC
                    complexes. Nature 1995;375:148-51.  DOI  PubMed
   36   37   38   39   40   41   42   43   44   45   46