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45.  Saiki  Y,  Ishimaru  S,  Mimori  K,  Takatsuno  Y,  Nagahara  M,   and  is  regulated  by  the  microenvironment.  Nat  Cell  Biol
               Ishii  H,  Yamada  K,  Mori  M.  Comprehensive  analysis  of  the   2010;12:468-76.
               clinical  signifi cance  of  inducing  pluripotent  stemness-related   62.  Butler  JM,  Kobayashi  H,  Rafi i  S.  Instructive  role  of  the
               gene  expression  in  colorectal  cancer  cells.  Ann  Surg  Oncol   vascular  niche  in  promoting  tumour  growth  and  tissue  repair
               2009;16:2638-44.                                   by angiocrine factors. Nat Rev Cancer 2010;10:138-46.
            46.  Schofi eld   R.  The   relationship   between   the   spleen   63.  Calabrese  C,  Poppleton  H,  Kocak  M,  Hogg  TL,  Fuller  C,
               colony-forming  cell  and  the  haemopoietic  stem  cell.   Hamner  B,  Oh  EY,  Gaber  MW,  Finklestein  D,  Allen  M,
               Blood Cells 1978;4:7-25.                           Frank A, Bayazitov IT, Zakharenko SS, Gajjar A, Davidoff A,
            47.  Moore KA, Lemischka IR. Stem cells and their niches. Science   Gilbertson RJ. A perivascular niche for brain tumor stem cells.
               2006;311:1880-5.                                   Cancer Cell 2007;11:69-82.
            48.  Sato  T,  van  Es  JH,  Snippert  HJ,  Stange  DE,  Vries  RG,   64.  Krishnamurthy S, Dong Z, Vodopyanov D, Imai A, Helman JI,
               van den Born M, Barker N, Shroyer NF, van de Wetering M,   Prince  ME,  Wicha  MS,  Nor  JE.  Endothelial  cell-initiated
               Clevers  H.  Paneth  cells  constitute  the  niche  for  Lgr5  stem   signaling  promotes  the  survival  and  self-renewal  of  cancer
               cells in intestinal crypts. Nature 2011;469:415-8.  stem cells. Cancer Res 2010;70:9969-78.
            49.  Shinagawa  K,  Kitadai  Y,  Tanaka  M,  Sumida  T,  Kodama  M,   65.  Lu J, Ye X, Fan F, Xia L, Bhattacharya R, Bellister S, Tozzi F,
               Higashi  Y,  Tanaka  S,  Yasui  W,  Chayama  K.  Mesenchymal   Sceusi E, Zhou Y, Tachibana I, Maru DM, Hawke DH, Rak J,
               stem cells enhance growth and metastasis of colon cancer. Int   Mani  SA,  Zweidler-McKay  P,  Ellis  LM.  Endothelial  cells
               J Cancer 2010;127:2323-33.                         promote  the  colorectal  cancer  stem  cell  phenotype  through  a
            50.  Orimo  A,  Gupta  PB,  Sgroi  DC,  Arenzana-Seisdedos  F,   soluble form of Jagged-1. Cancer Cell 2013;23:171-85.
               Delaunay  T,  Naeem  R,  Carey  VJ,  Richardson  AL,   66.  Liang  D,  Ma  Y,  Liu  J,  Trope  CG,  Holm  R,  Nesland  JM,
               Weinberg  RA.  Stromal  fi broblasts  present  in  invasive   Suo  Z.  The  hypoxic  microenvironment  upgrades  stem-like
               human  breast  carcinomas  promote  tumor  growth  and   properties of ovarian cancer cells. BMC Cancer 2012;12:201.
               angiogenesis through elevated SDF-1/CXCL12 secretion. Cell   67.  Ma  Y,  Liang  D,  Liu  J,  Axcrona  K,  Kvalheim  G,  Stokke  T,
               2005;121:335-48.                                   Nesland  JM,  Suo  Z.  Prostate  cancer  cell  lines  under  hypoxia
            51.  Quail  DF,  Joyce  JA.  Microenvironmental  regulation  of  tumor   exhibit greater stem-like properties. PLoS One 2011;6:e29170.
               progression and metastasis. Nat Med 2013;19:1423-37.  68.  Soeda A, Park M, Lee D, Mintz A, Androutsellis-Theotokis A,
            52.  Shinagawa  K,  Kitadai Y, Tanaka  M,  Sumida T,  Onoyama  M,   McKay  RD,  Engh  J,  Iwama  T,  Kunisada  T,  Kassam  AB,
               Ohnishi  M,  Ohara  E,  Higashi  Y,  Tanaka  S,  Yasui  W,   Pollack  IF,  Park  DM.  Hypoxia  promotes  expansion  of  the
               Chayama  K.  Stroma-directed  imatinib  therapy  impairs  the   CD133-positive  glioma  stem  cells  through  activation  of
               tumor-promoting effect of bone marrow-derived mesenchymal   HIF-1alpha. Oncogene 2009;28:3949-59.
               stem  cells  in  an  orthotopic  transplantation  model  of  colon   69.  Yeung  TM,  Gandhi  SC,  Bodmer  WF.  Hypoxia  and  lineage
               cancer. Int J Cancer 2013;132:813-23.              specifi cation  of  cell  line-derived  colorectal  cancer  stem  cells.
            53.  Li  HJ,  Reinhardt  F,  Herschman  HR,  Weinberg  RA.   Proc Natl Acad Sci U S A 2011;108:4382-7.
               Cancer-stimulated mesenchymal stem cells create a carcinoma   70.  Lovejoy  JC,  de  la  Bretonne  JA,  Klemperer  M,  Tulley  R.
               stem cell niche via prostaglandin E2 signaling. Cancer Discov   Abdominal  fat  distribution  and  metabolic  risk  factors:  effects
               2012;2:840-55.                                     of race. Metabolism 1996;45:1119-24.
            54.  Peng  Y,  Li  Z,  Yang  P,  Newton  IP,  Ren  H,  Zhang  L,  Wu  H,   71.  Vongsuvanh R, George J, Qiao L, van der Poorten D. Visceral
               Li  Z.  Direct  contacts  with  colon  cancer  cells  regulate  the   adiposity  in  gastrointestinal  and  hepatic  carcinogenesis.
               differentiation  of  bone  marrow  mesenchymal  stem  cells  into   Cancer Lett 2013;330:1-10.
               tumor  associated  fi broblasts.  Biochem  Biophys  Res  Commun   72.  Renehan  AG,  Tyson  M,  Egger  M,  Heller  RF,  Zwahlen  M.
               2014;451:68-73.                                    Body-mass index and incidence of cancer: a systematic review
            55.  Todaro  M,  Gaggianesi  M,  Catalano  V,  Benfante A,  Iovino  F,   and meta-analysis of prospective observational studies. Lancet
               Biffoni  M,  Apuzzo  T,  Sperduti  I,  Volpe  S,  Cocorullo  G,   2008;371:569-78.
               Gulotta G, Dieli F, De Maria R, Stassi G. CD44v6 is a marker   73.  Yamaji  T,  Iwasaki  M,  Sasazuki  S,  Tsugane  S.  Gender
               of  constitutive  and  reprogrammed  cancer  stem  cells  driving   difference  in  the  association  of  insulin  and  the  insulin-like
               colon cancer metastasis. Cell Stem Cell 2014;14:342-56.  growth factor axis with colorectal neoplasia. Int J Obes (Lond)
            56.  Lotti  F,  Jarrar  AM,  Pai  RK,  Hitomi  M,  Lathia  J,  Mace  A,   2012;36:440-7.
               Gantt  GA  Jr,  Sukhdeo  K,  DeVecchio  J,  Vasanji A,  Leahy  P,   74.  Michaud A,  Drolet  R,  Noel  S,  Paris  G,  Tchernof A.  Visceral
               Hjelmeland  AB,  Kalady  MF,  Rich  JN.  Chemotherapy   fat accumulation is an indicator of adipose tissue macrophage
               activates   cancer-associated   fi broblasts   to   maintain   infi ltration in women. Metabolism 2012;61:689-98.
               colorectal  cancer-initiating  cells  by  IL-17A.  J  Exp  Med   75.  Neels  JG,  Olefsky  JM.  Infl amed  fat:  what  starts  the  fi re?
               2013;210:2851-72.                                  J Clin Invest 2006;116:33-5.
            57.  Bienz  M,  Clevers  H.  Linking  colorectal  cancer  to  Wnt   76.  Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL,
               signaling. Cell 2000;103:311-20.                   Ferrante  AW  Jr,  Obesity  is  associated  with  macrophage
            58.  Clevers  H.  Wnt/beta-catenin  signaling  in  development  and   accumulation in adipose tissue. J Clin Invest 2003;112:1796-808.
               disease. Cell 2006;127:469-80.                 77.  Wellen  KE,  Hotamisligil  GS.  Obesity-induced  infl ammatory
            59.  Fearon  ER,  Vogelstein  B.  A  genetic  model  for  colorectal   changes in adipose tissue. J Clin Invest 2003;112:1785-8.
               tumorigenesis. Cell 1990;61:759-67.            78.  Ishino  K,  Mutoh  M,  Totsuka  Y,  Nakagama  H.  Metabolic
            60.  Le  NH,  Franken  P,  Fodde  R.  Tumour-stroma  interactions  in   syndrome: a novel high-risk state for colorectal cancer. Cancer
               colorectal  cancer:  converging  on  beta-catenin  activation  and   Lett 2013;334:56-61.
               cancer stemness. Br J Cancer 2008;98:1886-93.  79.  Bartucci M, Svensson S, Ricci-Vitiani L, Dattilo R, Biffoni M,
            61.  Vermeulen L, De Sousa EM, van der Heijden M, Cameron K,   Signore M, Ferla R, De Maria R, Surmacz E. Obesity hormone
               de  Jong  JH,  Borovski  T,  Tuynman  JB,  Todaro  M,  Merz  C,   leptin induces growth and interferes with the cytotoxic effects
               Rodermond  H,  Sprick  MR,  Kemper  K,  Richel  DJ,  Stassi  G,   of 5-fl uorouracil in colorectal tumor stem cells.  Endocr Relat
               Medema  JP.  Wnt  activity  defi nes  colon  cancer  stem  cells   Cancer 2010;17:823-33.

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