Page 51 - Read Online
P. 51

Page 14 of 14      Tosato et al. J Cancer Metastasis Treat 2021;7:52  https://dx.doi.org/10.20517/2394-4722.2021.120

               85.       Schliemann C, Bieker R, Thoennissen N, et al. Circulating angiopoietin-2 is a strong prognostic factor in acute myeloid leukemia.
                    Leukemia 2007;21:1901-6.  DOI  PubMed
               86.       Rouault-Pierre K, Lopez-Onieva L, Foster K, et al. HIF-2α protects human hematopoietic stem/progenitors and acute myeloid
                    leukemic cells from apoptosis induced by endoplasmic reticulum stress. Cell Stem Cell 2013;13:549-63.  DOI  PubMed
               87.       Velasco-Hernandez T, Hyrenius-Wittsten A, Rehn M, Bryder D, Cammenga J. HIF-1α can act as a tumor suppressor gene in murine
                    acute myeloid leukemia. Blood 2014;124:3597-607.  DOI  PubMed
               88.       Vukovic M, Guitart AV, Sepulveda C, et al. Hif-1α and Hif-2α synergize to suppress AML development but are dispensable for
                    disease maintenance. J Exp Med 2015;212:2223-34.  DOI  PubMed  PMC
               89.       Bellamy WT, Richter L, Frutiger Y, Grogan TM. Expression of vascular endothelial growth factor and its receptors in hematopoietic
                    malignancies. Cancer Res 1999;59:728-33.  PubMed
               90.       Hassan HT, Zander A. Stem cell factor as a survival and growth factor in human normal and malignant hematopoiesis. Acta
                    Haematol 1996;95:257-62.  DOI  PubMed
               91.       Poulos MG, Gars EJ, Gutkin MC, et al. Activation of the vascular niche supports leukemic progression and resistance to
                    chemotherapy. Exp Hematol 2014;42:976-986.e3.  DOI  PubMed  PMC
               92.       Ossenkoppele GJ, Breems DA, Stuessi G, et al; Dutch-Belgian Hemato-Oncology Cooperative Group (HOVON) and Swiss Group
                    for Clinical Cancer Research (SAKK). Lenalidomide added to standard intensive treatment for older patients with AML and high-risk
                    MDS. Leukemia 2020;34:1751-9.  DOI  PubMed
               93.       Saito Y, Uchida N, Tanaka S, et al. Induction of cell cycle entry eliminates human leukemia stem cells in a mouse model of AML.
                    Nat Biotechnol 2010;28:275-80.  DOI  PubMed  PMC
               94.       Uy GL, Rettig MP, Motabi IH, et al. A phase 1/2 study of chemosensitization with the CXCR4 antagonist plerixafor in relapsed or
                    refractory acute myeloid leukemia. Blood 2012;119:3917-24.  DOI  PubMed  PMC
               95.       Abraham M, Klein S, Bulvik B, et al. The CXCR4 inhibitor BL-8040 induces the apoptosis of AML blasts by downregulating ERK,
                    BCL-2, MCL-1 and cyclin-D1 via altered miR-15a/16-1 expression. Leukemia 2017;31:2336-46.  DOI  PubMed
               96.       Jin L, Hope KJ, Zhai Q, Smadja-Joffe F, Dick JE. Targeting of CD44 eradicates human acute myeloid leukemic stem cells. Nat Med
                    2006;12:1167-74.  DOI  PubMed
               97.       Jacamo R, Chen Y, Wang Z, et al. Reciprocal leukemia-stroma VCAM-1/VLA-4-dependent activation of NF-κB mediates
                    chemoresistance. Blood 2014;123:2691-702.  DOI  PubMed  PMC
               98.       Kannan S, Sutphin RM, Hall MG, et al. Notch activation inhibits AML growth and survival: a potential therapeutic approach. J Exp
                    Med 2013;210:321-37.  DOI  PubMed  PMC
               99.       Laranjeira AB, Yang SX. Therapeutic target discovery and drug development in cancer stem cells for leukemia and lymphoma: from
                    bench to the clinic. Expert Opin Drug Discov 2016;11:1071-80.  DOI  PubMed
               100.      Granados-Principal S, Liu Y, Guevara ML, et al. Inhibition of iNOS as a novel effective targeted therapy against triple-negative
                    breast cancer. Breast Cancer Res 2015;17:25.  DOI  PubMed  PMC
               101.      Karp JE, Gojo I, Pili R, et al. Targeting vascular endothelial growth factor for relapsed and refractory adult acute myelogenous
                    leukemias: therapy with sequential 1-beta-d-arabinofuranosylcytosine, mitoxantrone, and bevacizumab.  Clin Cancer Res
                    2004;10:3577-85.  DOI  PubMed
               102.      Ossenkoppele GJ, Stussi G, Maertens J, et al. Addition of bevacizumab to chemotherapy in acute myeloid leukemia at older age: a
                    randomized phase 2 trial of the Dutch-Belgian Cooperative Trial Group for Hemato-Oncology (HOVON) and the Swiss Group for
                    Clinical Cancer Research (SAKK). Blood 2012;120:4706-11.  DOI  PubMed
               103.      Müller A, Lange K, Gaiser T, et al. Expression of angiopoietin-1 and its receptor TEK in hematopoietic cells from patients with
                    myeloid leukemia. Leuk Res 2002;26:163-8.  DOI  PubMed
               104.      Reikvam H, Hatfield KJ, Lassalle P, Kittang AO, Ersvaer E, Bruserud Ø. Targeting the angiopoietin (Ang)/Tie-2 pathway in the
                    crosstalk between acute myeloid leukaemia and endothelial cells: studies of Tie-2 blocking antibodies, exogenous Ang-2 and
                    inhibition of constitutive agonistic Ang-1 release. Expert Opin Investig Drugs 2010;19:169-83.  DOI  PubMed
               105.      Lane SW, Wang YJ, Lo Celso C, et al. Differential niche and Wnt requirements during acute myeloid leukemia progression. Blood
                    2011;118:2849-56.  DOI  PubMed  PMC
   46   47   48   49   50   51   52   53   54   55   56